Results 141 to 150 of about 1,106 (217)
Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib +3 more
wiley +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aim To provide a practical guide on when to suspect endogenous hypercortisolism, how to use the overnight 1‐mg dexamethasone suppression test (DST) for targeted case‐finding, and which patients are most likely to benefit from treatment.
Juan Pablo Frias
wiley +1 more source
Mediator bias and methodological limitations in the evaluation of physiological CTG interpretation
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Boujenah Jérémy
wiley +1 more source
Equine Veterinary Education, EarlyView.Summary Melanomas are among the most frequent neoplasms in grey horses. Deep perirectal melanomas, however, are uncommon and challenging to excise due to their proximity to the peritoneal reflection. This report describes the successful standing removal of a large (16 × 8 × 6 cm) perirectal melanoma firmly adherent to the dorsal rectal wall in a 19 ...
R. Becker, C. Koch, M. de Preux
wiley +1 more source
Anaesthetic management of a horse with acute kidney injury
Equine Veterinary Education, EarlyView.Summary Anaesthetic management of animals with acute kidney injuries (AKI) is complex and poses considerable risk. There are no publications describing management of anaesthetised horses with AKI. Perioperative and anaesthetic care of a Thoroughbred filly presented with traumatic injuries and subsequent AKI is described.
C. T. Quinn, K. J. Hughes, A. N. Walton
wiley +1 more source
Headache: The Journal of Head and Face Pain, EarlyView.Plain Language Summary Spontaneous intracranial hypotension (SIH) is caused by leakage of cerebrospinal fluid and often produces symptoms that worsen when standing, which may resemble autonomic disorders (conditions related to blood flow and heart rate).
Woo‐Seok Ha +4 more
wiley +1 more source
Predictive factors of epidural blood patch success in intracranial hypotension syndrome
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objective This study aimed to identify predictors of epidural blood patch (EBP) success in patients with intracranial hypotension syndrome. Background The epidural blood patch remains the gold standard treatment for intracranial hypotension syndrome, yet its effectiveness varies, and predictors of sustained success remain uncertain. Methods We
Anna Le Moal‐Baczynski +13 more
wiley +1 more source
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Background Moderate‐to‐severe thrombocytopenia (platelet count < 100 × 109/L) occurs in fewer than 1% of pregnancies, posing management challenges, particularly surrounding eligibility for neuraxial anesthesia. Although recent anesthesia guidelines recommend a platelet threshold ≥ 70 × 109/L, outcomes data applying these recommendations in ...
Mackenzie E. Lemieux, Ming Y. Lim
wiley +1 more source
Guideline for the Comprehensive Perioperative Management of Older Patients With Lung Cancer (2025)
Journal of Evidence-Based Medicine, EarlyView.ABSTRACT With the accelerating population aging, the number of older adult patients with lung cancer continues to increase. These patients often present with multiple chronic diseases and geriatric syndromes, resulting in more complex perioperative management and significantly increased surgical risks.
Daiping Li +6 more
wiley +1 more source