Results 41 to 50 of about 3,673 (162)

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Prominent Expression of Xenobiotic Efflux Transporters in Mouse Extraembryonic Fetal Membranes Compared with Placenta [PDF]

open access: yesDrug Metabolism and Disposition, 2008
Fetal exposure to xenobiotics can be restricted by transporters at the interface between maternal and fetal circulation. Previous work identified transporters in the placenta; however, less is known about the presence of these transporters in the fetal membranes (i.e., yolk sac and amniotic membranes). The purpose of this study was to quantify mRNA and
Lauren M, Aleksunes   +2 more
openaire   +2 more sources

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos   +8 more
wiley   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

open access: yesAndrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen   +5 more
wiley   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick   +7 more
wiley   +1 more source

Laboratory Biology, Immature and Adult Morphology of Trichopria drosophilae (Perkins) (Hymenoptera: Diapriidae), Parasitoids of Drosophila Flies

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
This study investigates the laboratory biology and morphology of the parasitoid Trichopria drosophilae, which targets Drosophila flies, including the invasive Drosophila suzukii. Key findings include a detailed description of the parasitoid's egg, three larval instars, and pupal stage, as well as unique behaviors such as siblicide and encapsulation in ...
Alex Gumovsky   +3 more
wiley   +1 more source

Extraembryonic Membranes and Placentation in the Mexican Snake Conopsis lineata

open access: yesJournal of Morphology
ABSTRACT Extraembryonic membranes provide protection, oxygen, water, and nutrients to developing embryos, and their study generates information on the origin of the terrestrial egg and the evolution of viviparity. In this research, the morphology of the extraembryonic membranes and the types of placentation in the
Cecilia de Dios‐Arcos   +1 more
openaire   +2 more sources

Imaging and genetic toolbox to study Arabidopsis embryogenesis

open access: yesNew Phytologist, Volume 250, Issue 3, Page 1483-1491, May 2026.
Summary Embryogenesis in the model plant Arabidopsis thaliana provides a framework for understanding how cell polarity and patterning coordinate with hormonal signalling to establish the plant body plan. Following fertilisation, the zygote divides asymmetrically to generate apical and basal lineages, establishing the apical–basal axis that defines ...
David Babić   +2 more
wiley   +1 more source

Spatiotemporal segmentation of contraction waves in the extra-embryonic membranes of the red flour beetle

open access: yesBMC Bioinformatics
Background In this paper, we introduce an image analysis approach for spatiotemporal segmentation, quantification, and visualization of movement or contraction patterns in 2D+t and 3D+t microscopy recordings of biological tissues. The development of this
Marc Pereyra   +6 more
doaj   +1 more source

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