One‐year follow‐up after fractionated ultra‐high‐dose‐rate FLASH radiotherapy in patient with extramammary Paget disease of the scrotum [PDF]
An elderly male patient with extramammary Paget disease of the scrotum and multiple metastases was treated with fractionated FLASH‐RT (40 Gy in 5 fractions) in the scrotal lesion. Abstract Objective Ultrahigh‐dose‐rate radiotherapy (FLASH‐RT) has been shown to reduce radiation‐induced normal tissue injury in preclinical studies.
Luo H +14 more
europepmc +2 more sources
The role of human microbiota in breast cancer pathogenesis and treatment
The human microbiota contributes to breast cancer pathogenesis and treatment response through interactions involving the oral, gut, and breast microbial niches. (Left) Multi‐site dysbiosis is characterized by altered microbial composition and abundance across different anatomical sites.
Jie Qiu +9 more
wiley +1 more source
Background The rise of multiple primary malignant neoplasms (MPMNs) necessitates exploration. MPMNs represent 18% of U.S. cancers. Breast cancer is the predominant malignancy among female Americans.
Bei Sun +6 more
doaj +1 more source
Scrotal squamous cell carcinoma: Two HPV‐negative cases with probable UV‐ induced pathogenesis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Daniel Craus +7 more
wiley +1 more source
The diagnostic challenge of primary adenocarcinoma of the vulva: a case report
The diagnosis and classification of primary adenocarcinoma of the vulva is a complicated and understudied area, as this is a rare histological subtype of vulvar cancers.
Chun Yuen Chow +3 more
doaj +1 more source
Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley +1 more source
Advanced Extramammary Paget's Disease of the Groin, Penis, and Scrotum
Extramammary Paget's disease (EMPD) is a rare intraepithelial malignancy arising in areas rich in apocrine glands, such as the perineum, vulva, axilla, scrotum, and penis.
Karlos Z. Oregel +13 more
core +1 more source
Pigmented Basal Cell Carcinoma Mimicking Melanoma in the Anal Area: A Case Report
ABSTRACT Early evaluation of persistent perianal lesions is essential even when symptoms appear mild or patients feel embarrassed to seek care. Pigmented basal cell carcinoma in this region is rare and may mimic melanoma clinically. Ongoing histopathological and immunohistochemical assessment is crucial to ensure correct diagnosis and timely surgical ...
Farnaz Araghi +3 more
wiley +1 more source
Mammary and extramammary Paget's disease [PDF]
Mammary and extramammary Paget's disease are uncommon intraepithelial adenocarcinomas. Both conditions have similar clinical features, which mimic inflammatory and infective diseases. Histological diagnostic confusion can arise between Paget's disease and other neoplastic conditions affecting the skin, with the most common differential diagnoses being ...
J, Lloyd, A M, Flanagan
openaire +2 more sources
Lichenoid lesions around the anus: An unusual site of Hailey–Hailey disease
The anal region is an unusual site of Hailey–Hailey disease. It manifests with lichenoid lesions with crusted erosions around the anus. It should be differentiated from condylomata acuminata, extramammary Paget disease, and bowenoid papulosis.
Fatma Hammami +6 more
doaj +1 more source

