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Plastic and Reconstructive Surgery, 1982
Extramammary Paget's disease is an in situ skin and mucosal carcinoma frequently associated with and probably arising in a subjacent or regionally proximate carcinoma. Microscopic spread of tumor cells almost always extends beyond clinically apparent disease.
G H, Pitman +3 more
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Extramammary Paget's disease is an in situ skin and mucosal carcinoma frequently associated with and probably arising in a subjacent or regionally proximate carcinoma. Microscopic spread of tumor cells almost always extends beyond clinically apparent disease.
G H, Pitman +3 more
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Recent treatment and prognosis in 643 patients with extramammary Paget's disease
Experimental DermatologyInformation about extramammary Paget's (EMPD) treatment is limited because of the rarity of the disease. The prognosis differs between in situ EMPD and invasive EMPD; therefore, therapy should be planned according to the disease stage.
Naohito Hatta +20 more
semanticscholar +1 more source
Clinics in Dermatology, 1993
E xtramammary Paget’s disease (EMPD) is an epithelial disorder usually observed in cutaneous apocrine gland-bearing regions. This condition may be associated with either subjacent or distant malignancies or may potentially be an invasive adenocarcinoma sui gene+. Clinically it is usually recognized as a nonhealing eczematous lesion.
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E xtramammary Paget’s disease (EMPD) is an epithelial disorder usually observed in cutaneous apocrine gland-bearing regions. This condition may be associated with either subjacent or distant malignancies or may potentially be an invasive adenocarcinoma sui gene+. Clinically it is usually recognized as a nonhealing eczematous lesion.
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Nishi Nihon Hifuka, 1979
外陰部ページェット病の7例について, 電顕的, 酵素組織化学的検索をおこない, 表皮のページェット細胞と下床の腺癌の関係, ページェット細胞の本態と由来について考察した。表皮のページェット細胞と下床の腺癌の分化度の差については, 表皮内においてページェット細胞の分化にたいし何らかの抑制が働いている可能性が示唆された。下床の腺癌はあきらかにアポクリン腺癌であり, 表皮のページェット細胞も分化度は低いが, 自験例はすべてアポクリン腺への分化を示していると考えられた。
Masayuki NISHIMURA +3 more
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外陰部ページェット病の7例について, 電顕的, 酵素組織化学的検索をおこない, 表皮のページェット細胞と下床の腺癌の関係, ページェット細胞の本態と由来について考察した。表皮のページェット細胞と下床の腺癌の分化度の差については, 表皮内においてページェット細胞の分化にたいし何らかの抑制が働いている可能性が示唆された。下床の腺癌はあきらかにアポクリン腺癌であり, 表皮のページェット細胞も分化度は低いが, 自験例はすべてアポクリン腺への分化を示していると考えられた。
Masayuki NISHIMURA +3 more
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Extramammary Paget's Disease: A Review of the Literature Part II: Treatment and Prognosis.
Dermatologic Surgery, 2019BACKGROUND Extramammary Paget's disease (EMPD) is a rare malignancy with unclear pathophysiology that occurs predominantly on apocrine-rich skin. Surgery is the treatment of choice; however, procedures tend to be extensive and associated with a high rate
C. Morris, E. Hurst
semanticscholar +1 more source
Current Management and Treatment of Extramammary Paget’s Disease
Current Treatment Options in Oncology, 2022Hiroki Hashimoto, Takamichi Ito
semanticscholar +1 more source
2018
Extramammary Paget’s disease (EMPD) is a rare, slow-growing intraepithelial adenocarcinoma typically localized to areas of apocrine gland distribution outside the mammary glands. EMPD typically involves the vulva, perianal area, and male genitalia, with rare sites including the thighs, buttocks, axilla, eyelids, and external ear canal.
Nathalie C. Zeitouni, Jose A. Cervantes
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Extramammary Paget’s disease (EMPD) is a rare, slow-growing intraepithelial adenocarcinoma typically localized to areas of apocrine gland distribution outside the mammary glands. EMPD typically involves the vulva, perianal area, and male genitalia, with rare sites including the thighs, buttocks, axilla, eyelids, and external ear canal.
Nathalie C. Zeitouni, Jose A. Cervantes
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Southern medical journal, 2000
Extramammary Paget's disease (EMPD) is an uncommon but distinctive tumor. The lesion is defined as an intra-epidermal neoplasm. The lesion may be accompanied by an invasive adenocarcinoma or in situ adenocarcinoma of apocrine glands. Visceral carcinoma may also coexist or develop.
N J, Mehta, R, Torno, T, Sorra
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Extramammary Paget's disease (EMPD) is an uncommon but distinctive tumor. The lesion is defined as an intra-epidermal neoplasm. The lesion may be accompanied by an invasive adenocarcinoma or in situ adenocarcinoma of apocrine glands. Visceral carcinoma may also coexist or develop.
N J, Mehta, R, Torno, T, Sorra
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2014
Extramammary Paget’s disease, originally described by Crocker in 1889, is a rare apocrine adenocarcinoma that appears in the epidermis and from there may extend into the epithelial structures of adnexa and dermis. The pathogenesis of EMPD is still controversial. There are two different forms of EMPD with distinct pathogenetic mechanisms.
Irina Margaritescu, A. Doru Chirita
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Extramammary Paget’s disease, originally described by Crocker in 1889, is a rare apocrine adenocarcinoma that appears in the epidermis and from there may extend into the epithelial structures of adnexa and dermis. The pathogenesis of EMPD is still controversial. There are two different forms of EMPD with distinct pathogenetic mechanisms.
Irina Margaritescu, A. Doru Chirita
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KS-EMPD-1: a novel cell line of primary extramammary Paget’s disease
Human Cell, 2023Takamichi Ito +4 more
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