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Extramammary Paget Disease [PDF]
Extramammary Paget disease is an intraepidermal adenocarcinoma, most often limited to the epidermis, with typical cases affecting genital skin. When limited to the epidermis, primary extramammary Paget disease is not life-threatening, but invasive disease may portend a poor prognosis.
David G Brodland
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Journal of the American Academy of Dermatology, 1986
Summary Extramammary Paget's disease remains a difficult clinical diagnosis and, though biopsy readily establishes the presence of a tumour with an intraepidermal spread, this needs further study so that other tumours with a similar pattern of spread may be excluded. We advocate the use of a panel of readily available peroxidase-labelled antisera to
P P, Anthony, K, Freeman, A P, Warin
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Summary Extramammary Paget's disease remains a difficult clinical diagnosis and, though biopsy readily establishes the presence of a tumour with an intraepidermal spread, this needs further study so that other tumours with a similar pattern of spread may be excluded. We advocate the use of a panel of readily available peroxidase-labelled antisera to
P P, Anthony, K, Freeman, A P, Warin
openaire +4 more sources
Extramammary Paget disease of the vulva
Seminars in Diagnostic Pathology, 2021Extramammary Paget disease (EMPD) is a rare neoplasm with uncertain histogenesis, usually presenting in the anogenital area, most commonly in the vulva. The disease is characterized by slow grow and high recurrence rates. This article reviews the epidemiological, clinical, morphological, genetic and treatment features of EMPD of the vulva reported in ...
Anastasia Konstantinova +1 more
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New England Journal of Medicine, 2017
An 89-year-old man presented with a 1-year history of a nonhealing groin rash that did not respond to antibiotics, antifungal agents, or glucocorticoids. A diagnosis of extramammary Paget’s disease was made by means of a skin biopsy.
Sarah H, Mehrtens, Sriramulu, Tharakaram
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An 89-year-old man presented with a 1-year history of a nonhealing groin rash that did not respond to antibiotics, antifungal agents, or glucocorticoids. A diagnosis of extramammary Paget’s disease was made by means of a skin biopsy.
Sarah H, Mehrtens, Sriramulu, Tharakaram
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Mammary and extramammary Paget's disease
Journal of the European Academy of Dermatology and Venereology, 2007AbstractPaget's disease is an intra‐epidermal adenocarcinoma seen over the nipple/areola (mammary Paget's disease) or in extramammary body zones, such as the anogenital and perineal skin and the axilla. Mammary and extramammary Paget's disease share many common clinicopathological features but also show several differences, namely, with regard to ...
Jean Kanitakis
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Hematology/Oncology Clinics of North America, 2019
Extramammary Paget disease (EMPD) is a rare cutaneous malignancy most commonly affecting the genitals, perineum, and perianal area of the elderly. Despite its rarity, to those impacted, the disease and its treatment can have a tremendous impact on quality of life.
Mackenzie, Asel, Nicole R, LeBoeuf
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Extramammary Paget disease (EMPD) is a rare cutaneous malignancy most commonly affecting the genitals, perineum, and perianal area of the elderly. Despite its rarity, to those impacted, the disease and its treatment can have a tremendous impact on quality of life.
Mackenzie, Asel, Nicole R, LeBoeuf
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The American Journal of Surgery, 1957
Abstract A case of extramammary Paget's disease of the perianal skin with widespread metastases in a fifty-nine year old white man is presented. This represents approximately the twentyninth recorded example of this disease, and only the second in which widespread metastatic disease has been unequivocally demonstrated.
E R, FISHER, F D, BEYER
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Abstract A case of extramammary Paget's disease of the perianal skin with widespread metastases in a fifty-nine year old white man is presented. This represents approximately the twentyninth recorded example of this disease, and only the second in which widespread metastatic disease has been unequivocally demonstrated.
E R, FISHER, F D, BEYER
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Depigmented extramammary Paget's disease
British Journal of Dermatology, 2004Depigmented extramammary Paget's disease (EMPD) has been reported in a few cases. Depigmented macules or patches may be the only presenting sign or may coexist with the classical erythematous lesions.To investigate the occurrence rate and clinical presentation of depigmentation in EMPD.All pathology-proven cases of EMPD diagnosed in our department ...
C-C, Yang, J Y-Y, Lee, T-W, Wong
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Clinics in Dermatology, 1993
E xtramammary Paget’s disease (EMPD) is an epithelial disorder usually observed in cutaneous apocrine gland-bearing regions. This condition may be associated with either subjacent or distant malignancies or may potentially be an invasive adenocarcinoma sui gene+. Clinically it is usually recognized as a nonhealing eczematous lesion.
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E xtramammary Paget’s disease (EMPD) is an epithelial disorder usually observed in cutaneous apocrine gland-bearing regions. This condition may be associated with either subjacent or distant malignancies or may potentially be an invasive adenocarcinoma sui gene+. Clinically it is usually recognized as a nonhealing eczematous lesion.
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