Results 51 to 60 of about 1,270 (205)

A clinicopathological analysis of forkhead box A1 (FOXA1) and estrogen receptor alpha expression in extramammary Paget’s disease

Fujita Medical Journal, 2023
Objectives: Extramammary Paget’s disease (EMPD) is a neoplastic skin disease of unknown etiology. EMPD is frequently associated with forkhead box A1 (FOXA1) expression, which correlates with the expression of estrogen receptor alpha (ER). FOXA1 regulates
Chiho Sumitomo, Yohei Iwata, Masaru Arima, Kazumitsu Sugiura   +3 more
doaj   +1 more source

Extramammary Paget disease of the vulva with underlying mammary-like lobular carcinoma: a case report and review of the literature

, 2015
Extramammary Paget disease of the vulva accounts for 1%–2% of the neoplasms of the anogenital area. Very rarely, extramammary Paget disease of the vulva has been associated with an underlying mammary-like carcinoma, usually ductal, extremely rarely mixed
Milikowski, Clara, Yu, Wendong, Villada, Gabriel, Farooq, Uzma, Diaz, John Paul   +4 more
core   +1 more source

Treatment of Extramammary Paget Disease and the Role of Reflectance Confocal Microscopy: A Prospective Study

, 2021
BACKGROUND Extramammary Paget disease (EMPD) poses treatment challenges. Invasive and noninvasive treatment modalities exist with variable success reported. Reflectance confocal microscopy (RCM) is emerging as an adjuvant diagnostic tool.
Melissa Pulitzer, Travis Hollmann, Andrea Moy, Navarrete-Dechent, Cristian, Leitao, Mario M., Jr., Busam, Klaus J., Erlendsson, Andres M., Anthony M. Rossi, Aleissa, Saud, Andres M. Erlendsson, Klaus J. Busam, Lezcano, Cecilia, Miguel Cordova, Cordova, Frank, Cristian Navarrete-Dechent, Cecilia Lezcano, Lee, Erica H., Erica H. Lee, Hollmann, Travis, Pulitzer, Melissa, Brian P. Hibler, Frank Cordova, Mario M. Leitao, Rossi, Anthony M., Polansky, Max, Max Polansky, Saud Aleissa, Hibler, Brian P., Cordova, Miguel, Moy, Andrea   +29 more
core   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

Chemistry – A European Journal, Volume 32, Issue 17, 5 May 2026.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Multifocal extramammary Paget’s disease-associated adenocarcinoma: a rare condition of flexoral skin of multiple sites [PDF]

, 2016
Extramammary Paget disease (EMPD) is a rare malignant neoplasm of apocrine sweat glands that is morphologically and histologically identical to Paget disease of the breast.
Rapini, Ronald, Wolf, Kristin, Mutyambizi, Kudakwashe, Stewart, Larissa   +3 more
core   +1 more source

Primary vulvar Paget disease – the importance of clinical suspicion [PDF]

, 2017
Extramammary Paget disease of the vulva is a rare condition that accounts for only 1-2% of vulvar malignancies and represents a frequent cause of misdiagnosis. It is most commonly seen in postmenopausal women. Clinically it is similar to Paget disease of
Mota, Fernando, Marques, Claudia, Selores, Manuela, Horta, Miguel, Foreid, Susan   +4 more
core   +3 more sources

Double Lotus Petal Flaps for Large Perianal Defect Reconstruction After Multistage Extramammary Paget Resection

Plastic and Reconstructive Surgery, Global Open
Summary:. Several reconstructive procedures have been documented for large perianal defects after extensive surgical resection. The lotus petal flap (LPF) is a fasciocutaneous flap, the use of which remains limited compared with alternative surgical ...
Edward T.C. Dong, BSc, Frédéric Ris, MD, Carlo M. Oranges, MD, PhD   +2 more
doaj   +1 more source

Nonmass‐Forming Type Anocanal Cancer With Pagetoid Spread With a Challenging Differential Diagnosis: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Pagetoid spread (PS) of anorectal cancer is relatively rare and is associated with poor prognosis compared with Extramammary Paget disease. It is therefore essential to accurately differentiate between the two entities. In PS cases, the primary tumor lesion is usually obvious; however, this is not the case in nonmass‐forming type anorectal ...
Mizunori Yaegashi, Ryo Sugimoto, Hiroaki Shimada, Akira Sasaki   +3 more
wiley   +1 more source

A Multifaceted Holistic Review of the Literature on Scar Dermatoses

International Wound Journal, Volume 23, Issue 5, May 2026.
ABSTRACT Many cutaneous diseases originate or manifest in scars. Scars are areas of compromised skin, which renders them a vulnerable cutaneous district for diseases to develop. The pathophysiology explaining why some dermatoses grow in scars is not yet thoroughly explored. The present study reviews the present literature on scar dermatoses.
Dana Maria Khoury, Elias El Tayar, Edward Eid, Firas F. Haddad, Ossama Abbas, Mazen Kurban   +5 more
wiley   +1 more source

Response to 5-Fluorouracil in Metastatic Extramammary Paget Disease of the Scrotum Presenting as Pancytopenia and Back Pain

, 2009
Extramammary Paget disease is a rare intraepithelial neoplasm of the vulvar, penoscrotal, or perianal skin. No effective therapies for metastatic disease have been reported, and prognosis for metastatic disease is poor.
K. M. Beleznay, M. A. Levesque, S. Gill
core   +1 more source