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Mammary and extramammary Paget's disease [PDF]
Mammary and extramammary Paget's disease are uncommon intraepithelial adenocarcinomas. Both conditions have similar clinical features, which mimic inflammatory and infective diseases. Histological diagnostic confusion can arise between Paget's disease and other neoplastic conditions affecting the skin, with the most common differential diagnoses being ...
J, Lloyd, A M, Flanagan
openaire +2 more sources
Practice Patterns in Extramammary Paget's Disease
ABSTRACT Background In patients with Extramammary Paget's Disease (EMPD), a rare intraepithelial adenocarcinoma, wide local excision (WLE) has historically been the standard of treatment despite high rates of positive margins and recurrence. Mohs micrographic surgery (MMS) has demonstrated superior outcomes, yet practice patterns vary due to limited ...
Yasmine Mohseni +4 more
wiley +1 more source
Objectives: Extramammary Paget’s disease (EMPD) is a neoplastic skin disease of unknown etiology. EMPD is frequently associated with forkhead box A1 (FOXA1) expression, which correlates with the expression of estrogen receptor alpha (ER). FOXA1 regulates
Chiho Sumitomo +3 more
doaj +1 more source
The clinical evidence and the role of imiquimod in the extramammary Paget disease [PDF]
Extramammary Paget disease is a rare disease. Different treatment options are used for its management, among them treatment with imiquimod. Our aim is to clarify the efficacy and safety of the use of topical imiquimod cream in the treatment of ...
Karachalios, Charalampos +4 more
core +1 more source
S1 guideline sweat gland carcinoma
Summary The current classification of sweat gland carcinomas is based on histomorphological characteristics and distinguishes between more than 20 entities. Most patients are older, but some subtypes also affect middle‐aged and younger patients. The majority of tumors arise de novo. Sweat gland carcinomas have nonspecific clinical features.
Mirjana Ziemer +19 more
wiley +1 more source
Summary:. Several reconstructive procedures have been documented for large perianal defects after extensive surgical resection. The lotus petal flap (LPF) is a fasciocutaneous flap, the use of which remains limited compared with alternative surgical ...
Edward T.C. Dong, BSc +2 more
doaj +1 more source
ABSTRACT Objective To examine the routes to penile cancer diagnosis and the role of penile biopsy. Materials and Methods This retrospective observational study from a tertiary referral center included 625 patients referred as urgent suspected penile cancer within the Danish Cancer Patient Pathway (CPP) and 216 patients undergoing penile biopsy outside ...
Christian Raun Boné +1 more
wiley +1 more source
Extramammary Paget disease of the vulva accounts for 1%–2% of the neoplasms of the anogenital area. Very rarely, extramammary Paget disease of the vulva has been associated with an underlying mammary-like carcinoma, usually ductal, extremely rarely mixed
Milikowski, Clara +4 more
core +1 more source
Extramammary Paget's disease with the appearance of a nodule: a case report
Background Extramammary Paget's disease (EMPD) remains a rare condition with only a limited number of cases reported in the literature. EMPD is mainly composed of intraepidermal Paget cells, and possesses variable clinical behaviors and histological ...
Yang Jian, Yang Wenlin, Wang Xia
doaj +1 more source
ABSTRACT Persistent treatment‐resistant anogenital plaques should not be repeatedly managed as chronic eczema without histopathological confirmation. Early biopsy of atypical or non‐resolving lesions facilitates timely diagnosis of Bowen disease, prevents prolonged diagnostic delay, and enables treatment before progression to invasive squamous cell ...
Shiwani Sharma Acharya +2 more
wiley +1 more source

