Results 81 to 90 of about 1,691 (202)

Perianal Pagetoid Intraepithelial Carcinoma

Case Reports in Gastroenterology, 2017
Extramammary Paget disease (EMPD) involving the perianal region is rare and challenging to manage. Primary EMPD involves stand-alone noninvasive lesions within the epidermis, while secondary EMPD involves phenotypically similar lesions derived from ...
Suanga Sisodia, Robin Boushey, Goo Lee, Celia Marginean, Marcio M. Gomes, Gaurav Bhattacharya, Kristopher Dennis   +6 more
doaj   +1 more source

The clinical evidence and the role of imiquimod in the extramammary Paget disease [PDF]

, 2014
Extramammary Paget disease is a rare disease. Different treatment options are used for its management, among them treatment with imiquimod. Our aim is to clarify the efficacy and safety of the use of topical imiquimod cream in the treatment of ...
Charalampos Karachalios, Christos Iavazzo, Fotinie Ntziora, Ioannis D. Gkegkes, Paraskevi Evangelia Iavazzo   +4 more
core   +1 more source

Curative Effect of Cutaneous Ulcer Wound Repair Through a Novel Liquid Dressing After HpD‐PDT Treatment of Extramammary Paget's Disease—A Prospective, Semi‐Lesion Controlled, Pilot Study

Journal of Cosmetic Dermatology, Volume 24, Issue 9, September 2025.
ABSTRACT Objective To evaluate the clinical efficacy and safety of a novel skin wound dressing in promoting the repair of the ulcer wound after the treatment of Extramammary Paget's Disease (EMPD) with Hematoporphyrin Derivative Photodynamic Therapy (HpD‐PDT).
Dixin Wang, Yan Zhao, Qihang Chang, Peiru Wang, Guolong Zhang, Xiuli Wang   +5 more
wiley   +1 more source

The evolving role of TRPS1 in dermatopathology: insights from the past 4 years [PDF]

Journal of Pathology and Translational Medicine
Over the past 4 years, trichorhinophalangeal syndrome type 1 (TRPS1) has rapidly gained attention among practicing pathologists, with numerous studies emerging that both support and question its diagnostic utility. Initially regarded as a highly specific
Mokhtar H. Abdelhammed, Woo Cheal Cho
doaj   +1 more source

CXCL13 and CCL21 Induce Tertiary Lymphoid Structures and Enhance the Efficacy of Immunotherapy for Melanoma

Cancer Science, Volume 116, Issue 8, Page 2075-2085, August 2025.
Plasma CCL21 levels were significantly increased in tertiary lymphoid structures (TLS)‐positive melanoma cases both before and after immune checkpoint inhibitors (ICI) treatment, while CXCL13 levels were significantly elevated after ICI treatment. We successfully induced TLS by co‐administering CXCL13 and CCL21 in a mouse melanoma model, clarifying ...
Maki Yoshimitsu, Motoki Nakamura, Shinji Kano, Tetsuya Magara, Hiroshi Kato, Aiko Sakai, Masaya Sugiyama, Masashi Mizokami, Akimichi Morita   +8 more
wiley   +1 more source

Patología no infecciosa de la vulva.Revisión de la literatura y puesta al día. [PDF]

, 2017
La vulva es el conjunto de los órganos genitales externos de la mujer y comprende el área topográfica delimitada por el monte de Venus anteriormente, el periné en su parte posterior, los pliegues inguinales a ambos lados y el anillo himeneal medialmente.
González Santana, Cintia
core  

Neoadjuvant use of Imiquimod Before Surgery in Extramammary Paget’s Disease [PDF]

, 2018
A doença de Paget extramamária (DPEM) é uma neoplasia maligna cutânea, rara, observada principalmente em mulheres caucasianas pós-menopausa. A cirurgia é o tratamento mais comum.
Azevedo, F., Costa e Silva, M., Costa, J. S., Costa, M. A., Lisboa, Carmen   +4 more
core   +2 more sources

Longstanding Perianal Ulcers

JEADV Clinical Practice, Volume 4, Issue 5, Page 1274-1277, December 2025.
Narachai Julanon, Thanaphon Anutraungkool, Sirawich Jessadapattarakul, Vincent Piguet   +3 more
wiley   +1 more source

Enhancing inguinal tumor treatment outcomes with a customized 3D‐printed bolus

Journal of Applied Clinical Medical Physics, Volume 26, Issue 7, July 2025.
Abstract Traditional boluses for pelvic lesions present challenges, including compromised skin dose coverage from large air gaps in treatment plans and increased uncertainties in treatment delivery due to variations in bolus fitting. This study evaluates the clinical benefits of a patient‐specific, 3D‐printed bolus (pBolus) in external beam radiation ...
Xing Li, Stephen Bhagroo, Fan‐Chi Su, Robabeh Rahimi, Jonathan Tward   +4 more
wiley   +1 more source

A Case of Concurrent Extramammary Paget Disease and Basal Cell Carcinoma of the Perianal Region

Plastic and Reconstructive Surgery, Global Open, 2020
Summary:. An 83-year-old Japanese man who had been aware of a tumor near his anus for 2 years underwent tumor resection. Although he was diagnosed with basal cell carcinoma (BCC), extramammary Paget disease (EMPD) was also accidentally found in the same ...
Natsuko Takahashi, MD, Yoshiyuki Okumura, MD, Eiichi Sawaragi, MD   +2 more
doaj   +1 more source