Results 91 to 100 of about 2,889 (184)
Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points. [PDF]
Haematopoiesis is the complex developmental process that maintains the turnover of all blood cell lineages. It critically depends on the correct functioning of rare, quiescent haematopoietic stem cells (HSCs) and more numerous, HSC-derived, highly ...
Blagborough, Andrew M +8 more
core +1 more source
Diabetes/Metabolism Research and Reviews, Volume 42, Issue 2, February 2026.ABSTRACT Clonal haematopoiesis (CH) has been recognized as an important interface between chronic inflammation, metabolic dysfunction, and the heightened cardiovascular risk observed in type 2 diabetes (T2D). CH arises from somatic mutations that give haematopoietic stem cells a competitive advantage and drive the expansion of pro‐inflammatory myeloid ...
Ludovica Migliozzi +3 more
wiley +1 more source
What Is Your Diagnosis? Splenic Mass in an African Pygmy Hedgehog
Veterinary Clinical Pathology, EarlyView.
Gabriela Hartmann +6 more
wiley +1 more source
eJHaem, Volume 7, Issue 1, February 2026.Abstract Background Immunophenotypically defined mixed‐phenotype acute leukemias (MPAL) are rare and remain a diagnostic and therapeutic dilemma. We aim to explore the clinicopathologic characteristics and oncological outcomes of these entities. Methods A total of 52 patients with immunophenotypically defined MPAL were identified from our pathology ...
Bo Zhang +5 more
wiley +1 more source
What's Your Diagnosis? A Case of Extreme Thrombocytosis in a Dog
Veterinary Clinical Pathology, EarlyView.
Stephanie F. Anderson +5 more
wiley +1 more source
eJHaem, Volume 7, Issue 1, February 2026.ABSTRACT Background PICALM::MLLT10‐positive T‐ALL is rare and associated with poor prognosis. Lineage switch to AML is exceptionally uncommon, particularly after long‐term remission. Case Presentation We report an adolescent PICALM::MLLT10‐positive T‐ALL with a cortical thymocyte, non‐ETP phenotype.
Machiko Kawamura +10 more
wiley +1 more source
Acute loss of TET function results in aggressive myeloid cancer in mice [PDF]
, 2015 TET-family dioxygenases oxidize 5-methylcytosine (5mC) in DNA, and exert tumour suppressor activity in many types of cancers. Even in the absence of TET coding region mutations, TET loss-of-function is strongly associated with cancer.
A Ciccia +64 more
core +1 more source
Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets
MedComm, Volume 7, Issue 2, February 2026.Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu +4 more
wiley +1 more source
Sepsis secondary to cystitis in a guinea pig (Cavia porcellus)
Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.Abstract Cystitis is a frequent, often chronic and recurrent disease in guinea pigs (Cavia porcellus). This report describes a case of a 2‐year‐old, entire, female Abyssinian guinea pig with fatal cystitis. The animal was presented with progressive chronic cystitis and had previously been treated with several antibiotics and analgesics.
Anika Mische +4 more
wiley +1 more source
Frontiers in EndocrinologyIntroductionAutosomal recessive osteopetrosis (ARO) is a rare genetic disease, characterized by increased bone density due to defective osteoclast function.
Sara Penna +33 more
doaj +1 more source