Results 111 to 120 of about 2,895 (221)

What Is Your Diagnosis? Splenic Mass in an African Pygmy Hedgehog

open access: yes
Veterinary Clinical Pathology, EarlyView.
Gabriela Hartmann   +6 more
wiley   +1 more source

Ten‐Year Outcome of a Patient With Concurrent Pelvic Myeloid Sarcoma and Underlying Chronic Myeloid Leukaemia in Chronic Phase: A Case Report and Literature Review

open access: yesCancer Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Myeloid sarcoma is a rare solid tumour of immature myeloid precursors occurring in an extramedullary site. It often presents significant diagnostic and therapeutic challenges to clinical haematologists. Case We describe a previously healthy patient who presented simultaneously with hyperleucocytic chronic myeloid leukaemia in ...
Kar Ying Yong   +3 more
wiley   +1 more source

What's Your Diagnosis? A Case of Extreme Thrombocytosis in a Dog

open access: yes
Veterinary Clinical Pathology, EarlyView.
Stephanie F. Anderson   +5 more
wiley   +1 more source

Unraveling the role of TP53 mutations in myeloproliferative neoplasms: Molecular mechanisms of leukemic transformation

open access: yesHemaSphere, Volume 10, Issue 3, March 2026.
Abstract TP53 mutations are found in over 50% of tumor types, including myeloproliferative neoplasms (MPNs). MPNs are characterized by a chronic phase, which may progress to secondary acute myeloid leukemia (sAML). Here, we discuss the physiological functions of p53 in hematopoiesis and its deregulation in MPNs.
Suzana da Silva‐Benedito   +6 more
wiley   +1 more source

Survival and Prognostic Factors of 215 Post‐Transplant Lymphoproliferative Disorders After Solid Organ Transplantations in a Finnish Nationwide Population‐Based Study Over 30 Years

open access: yesHematological Oncology, Volume 44, Issue 2, March 2026.
ABSTRACT Post‐transplant lymphoproliferative disorder (PTLD) is a rare, dreaded complication of organ transplantation with major clinical challenges. We conducted a nationwide population‐based study of all solid organ transplant (SOT) recipients (n = 6555), both adults and children, over a 30‐year period in Finland.
Terhi K. Friman   +11 more
wiley   +1 more source

TREATMENT OF MYELOFIBROSIS: PRESENT AND FUTURE

open access: yesHematology, Transfusion and Cell Therapy
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm characterised by stem cell-derived clonal myeloproliferation often, but not always, accompanied by JAK2, CALR or MPL mutations.
Birsen Sahip Yesiralioğlu
doaj   +1 more source

Research opportunities in loss of red blood cell mass in space flight [PDF]

open access: yes
Decreases of red blood cell mass and plasma volume have been observed consistently following manned space flights. Losses of red cell mass by United States astronauts have averaged 10 to 15% (range: 2 to 21%).
Fisher, K. D., Talbot, J. M.
core   +1 more source

Assessing The Role of Spleen in Development of Myeloid Bias Amongst Haematopoietic Stem Cells [PDF]

open access: yes
Myeloproliferative disorders are common in aged individuals, and ageing is associated with a skewing of haematopoiesis towards myeloid lineage. The spleen houses a distinct resident population of HSC primed for myelopoiesis which retain this myeloid bias
O'Neill, Helen C   +2 more
core   +1 more source

Preliminary Safety and Efficacy of Navitoclax Plus Ruxolitinib in Janus Kinase Inhibitor‐Naïve Patients With Myelofibrosis From the Multicenter, Open‐Label, Phase 2 Study (REFINE)

open access: yesHematological Oncology, Volume 44, Issue 2, March 2026.
ABSTRACT Myelofibrosis is characterized by perturbation of the JAK/STAT pathway and upregulation of anti‐apoptotic factors leading to myeloproliferation, bone marrow fibrosis (BMF), extramedullary hematopoiesis, splenomegaly, and cytopenias.
Francesco Passamonti   +16 more
wiley   +1 more source

The Global Burden of Leukemia, 1990–2021: A Systematic Analysis of Prevalence, DALYs, and Risk Factors From the Global Burden of Disease Study

open access: yesMed Research, Volume 2, Issue 1, Page 75-88, March 2026.
Using data from the Global Burden of Disease Study 2021, we systematically assessed leukemia prevalence and disability‐adjusted life years (DALYs) across 204 countries and territories from 1990 to 2021, stratified by subtype, demographics, and risk factors.
Yuping Wu   +8 more
wiley   +1 more source

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