Results 31 to 40 of about 11,984 (174)

Extramedullary haematopoiesis causing spinal cord compression [PDF]

, 2010
Extramedullary haematopoiesis (EMH) is a rare cause of spinal cord compression. When a patient with a haematological disorder that causes chronic anaemia (particularly thalassaemia) presents with neurological deficits referable to the spine, EMH with ...
Ismail, Farzanah, Huang, Lili, Ellemdin, Shiraz, Lockhat, Zarina I., Van der Linde, L.   +4 more
core   +1 more source

Metanephric adenoma with osseous metaplasia and bone marrow elements

Human Pathology: Case Reports, 2019
Metanephric adenoma is an uncommon benign renal neoplasm which typically occurs in the adult population. Although calcification is a common finding, osseous metaplasia is uncommon and may cause diagnostic difficulty on preoperative radiological imaging ...
Alessandro Pietro Aldera, MBChB, Jeff John, MBChB, Dharshnee Chetty, MBBCh FCPath, Dhirendra Govender, MBChB FRCPath PhD   +3 more
doaj   +1 more source

Giant splenic myelolipoma in a cat with hyperthyroidism

Journal of Feline Medicine and Surgery Open Reports, 2022
Case summary A 15 shorthair cat presented after having fallen down the stairs. Examination by the referring veterinarian had demonstrated tachycardia and a large abdominal mass. The cat was referred for investigations.
Kerry E Rolph, Beatriz Vidana, Elinor Field   +2 more
doaj   +1 more source

CT and MR findings in extramedullary haematopoiesis with biliary system encasement: A case report

, 2010
Extramedullary haematopoiesis is the production of blood elements outside the bone marrow cavity. In our case computed tomography and magnetic resonance imaging revealed the presence of a rare localization of extramedullary haematopoiesis with encasement
Alfredo La Fianza, Gloria Maccabelli, La Fianza, Alfredo, Maccabelli, Gloria, Lorella Torretta, van der Byl, Giulia, Calliada, Fabrizio, Giulia Van der Byl, Torretta, Lorella, Fabrizio Calliada   +9 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Extramedullary haematopoiesis within the thyroid cartilage

B-ENT, 2018
Extramedullary haematopoiesis within the thyroid cartilage. Problems/Objectives: Primitive non-neoplastic lesions of the laryngeal framework are quite rare. The aim of this study is to discuss the clinical and radiologic features of an incidental finding
D. Giordano, M. Zanichelli, M. Zanelli, A. Frasoldati, S. Bacciu, F. Avanzini, C. Pernice   +6 more
doaj   +2 more sources

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

The Pyruvate Kinase Deficiency Global Longitudinal (Peak) Registry: rationale and study design

BMJ Open, 2023
Introduction Pyruvate kinase (PK) deficiency is a rare, under-recognised, hereditary condition that leads to chronic haemolytic anaemia and potentially serious secondary complications, such as iron overload, cholecystitis, pulmonary hypertension and ...
Yan Yan, Junlong Li, D Mark Layton, Rachael F Grace, Vip Viprakasit, Eduard J van Beers, Joan-Lluis Vives Corrons, Bertil Glader, Andreas Glenthøj, Hitoshi Kanno, Kevin H M Kuo, Carl Lander, Dagmar Pospíŝilová, Audra N Boscoe, Chris Bowden, Paola Bianchi   +15 more
doaj   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source