Results 61 to 70 of about 2,889 (184)

The Calreticulin gene and myeloproliferative neoplasms [PDF]

, 2016
The Philadelphia negative myeloproliferative neoplasms include polycythaemia vera (PV), essential thrombocytopenia (ET) and primary myelofibrosis (PMF).
Clinton, Aoibhinn, McMullin, Mary Frances   +1 more
core   +1 more source

Increased Plasmodium chabaudi malaria mortality in mice with nutritional iron deficiency can be reduced by short-term adjunctive iron supplementation

Malaria Journal, 2018
Background Iron deficiency is the most widespread nutrient deficiency and an important cause of developmental impairment in children. However, some studies have indicated that iron deficiency can also protect against malaria, which is a leading cause of ...
Filip C. Castberg, Lasse Maretty, Trine Staalsoe, Casper Hempel, Erik Clasen-Linde, Lars Hviid, Jørgen A. L. Kurtzhals   +6 more
doaj   +1 more source

Presacral Myelolipoma [PDF]

, 2014
Many reports have described adrenal myelolipomas but there have been only a few reports of extra-adrenal myelolipomas. We describe a 74-year-old woman who came to our observa- tion for MRI of the lumbar spine for typical lumbar back pain.
FALANGA, Giorgia, GAGLIARDO, Cesare, LA TONA, Giuseppe, LAGALLA, Roberto, LO CASTO, Antonio, MIDIRI, Massimo, SUTERA, Raffaello   +6 more
core   +1 more source

Venetoclax combined with cladribine, idarubicin, cytarabine (CLIA‐VEN) results in higher remission rates over conventional 7 + 3 chemotherapy without increased toxicity in newly diagnosed acute myeloid leukaemia

British Journal of Haematology, EarlyView.
Summary Induction chemotherapy in fit de novo acute myeloid leukaemia (AML) patients has historically combined an anthracycline with standard‐dose cytarabine (‘7 + 3’) despite complete response (CR) rates of 50%–70%. In May 2023, our institution adopted the utilization of cladribine, cytarabine, idarubicin and venetoclax (CLIA‐VEN) for intensive ...
Benjamin J. Lee, Shawn P. Griffin, Jean Doh, Anthony Quach, Yujiao Sun, Piyatida Chumnumsiriwath, Stefan O. Ciurea, Jorge Ramos‐Perez, Polina Bellman, Deepa Jeyakumar, Piyanuch Kongtim, Kiran Naqvi   +11 more
wiley   +1 more source

Survival Motor Neuron (SMN) protein is required for normal mouse liver development [PDF]

, 2016
Spinal Muscular Atrophy (SMA) is caused by mutation or deletion of the survival motor neuron 1 (SMN1) gene. Decreased levels of, cell-ubiquitous, SMN protein is associated with a range of systemic pathologies reported in severe patients.
Francesco, M, Gillingwater, TH, Maxwell, GK, Parson, SH, Powis, RA, Szunyogova, E, Zhou, H   +6 more
core   +5 more sources

Extracellular vesicles originating from melanoma cells promote dysregulation in haematopoiesis as a component of cancer immunoediting

Journal of Extracellular Vesicles
Haematopoiesis dysregulation with the presence of immature myeloid and erythroid immunosuppressive cells are key characteristics of the immune escape phase of tumour development.
Doste R. Mamand, Safa Bazaz, Dara K. Mohammad, Xiuming Liang, Svetlana Pavlova, Carsten Mim, Susanne Gabrielsson, Joel Z. Nordin, Oscar P. B. Wiklander, Manuchehr Abedi‐Valugerdi, Samir EL‐Andaloussi   +10 more
doaj   +1 more source

Recurrent thoracic cord compression due to extramedullary haematopoiesis in thalassaemic patients–A case presentation and literature review

Journal of Orthopaedics, Trauma and Rehabilitation, 2019
Extramedullary haematopoesis (EMH) in thalassaemic patients to result in spinal cord compression is a rare phenomenon. EMH occurs as compensatory sequelae in those with chronic anaemia such as thalassaemia, other congenital haemolytic anaemia ...
Athena Cheuk Yiu Au, Chun Kong Wong, Ka Kin Li   +2 more
doaj   +1 more source

Assessment of measurable residual disease in ovarian tissue collected for fertility preservation in patients in remission from acute myeloid leukaemia: A pilot study

British Journal of Haematology, EarlyView.
Summary Allogeneic haematopoietic stem cell transplantation (ASCT) is a curative treatment for acute myeloid leukaemia (AML) but carries a high risk of gonadotoxicity. Ovarian tissue cryopreservation (OTC) offers a fertility preservation option, yet its safety in AML remains uncertain due to the risk of leukaemic cell reintroduction. The FERTILAM pilot
Augustin Boudry, Florian Chevillon, Alice Marceau‐Renaut, Thorsten Braun, Thomas Boyer, Nathalie Helevaut, Elise Fournier, Sandrine Geffroy, Nicolas Boissel, Emmanuelle Clappier, Claude Preudhomme, Nicolas Duployez, Catherine Poirot, Laurène Fenwarth   +13 more
wiley   +1 more source

Oxaliplatin-induced haematological toxicity and splenomegaly in mice.

PLoS ONE, 2020
PurposeHaematological toxicities occur in patients receiving oxaliplatin. Mild anaemia (grade 1-2) is a common side effect and approximately 90% of recipients develop measurable spleen enlargement.
Justin G Lees, Daniel White, Brooke A Keating, Mallory E Barkl-Luke, Preet G S Makker, David Goldstein, Gila Moalem-Taylor   +6 more
doaj   +1 more source

Donor Lymphocyte Infusion (DLI) for leukemia relapse: a revisit [PDF]

, 2000
published_or_final_versio
Au, WY, Chim, JCS, Kwong, YL, Lee, CK, Leung, AYH, Liang, RHS, Lie, AKW   +6 more
core