Results 61 to 70 of about 11,984 (174)

Increased Plasmodium chabaudi malaria mortality in mice with nutritional iron deficiency can be reduced by short-term adjunctive iron supplementation

Malaria Journal, 2018
Background Iron deficiency is the most widespread nutrient deficiency and an important cause of developmental impairment in children. However, some studies have indicated that iron deficiency can also protect against malaria, which is a leading cause of ...
Filip C. Castberg, Lasse Maretty, Trine Staalsoe, Casper Hempel, Erik Clasen-Linde, Lars Hviid, Jørgen A. L. Kurtzhals   +6 more
doaj   +1 more source

Bilateral lacrimal system involvement by sclerosing extramedullary hematopoietic tumor

, 2019
A 60-year-old man with myelofibrosis and extramedullary hematopoiesis was referred for evaluation of “swollen lacrimal glands.” Examination disclosed bilateral firm, immobile, nontender masses in the lacrimal sac fossa with no associated signs of ...
Bowman, Adam M., Shields, Marc D., Ghazi, Nicola G.   +2 more
core   +1 more source

The Spleen Plays No Role in Nephrotoxic Serum Nephritis, but Constitutes a Place of Compensatory Haematopoiesis.

PLoS ONE, 2015
BackgroundThe spleen has been implicated in the pathogenesis of immune-complex glomerulonephritis by initiating and resolving adaptive immune responses.
Katharina Artinger, Alexander H Kirsch, Ida Aringer, Corinna Schabhüttl, Alexander R Rosenkranz, Philipp Eller, Elena Rho, Kathrin Eller   +7 more
doaj   +1 more source

Pronounced Reductions in Plasma Citrulline Indicate Severe Intestinal Mucosal Barrier Injury During Induction Therapy for Pediatric Acute Myeloid Leukemia

European Journal of Haematology, EarlyView.
ABSTRACT Objectives Pediatric acute myeloid leukemia (AML) chemotherapy regimens are frequently burdened by fever episodes, systemic inflammation and bloodstream infections (BSI). Mucosal barrier injury may contribute to these complications, but its role in childhood AML remains uninvestigated.
Carla Warley Kjær, Maria Ebbesen Sørum, Silvia De Pietri, Claus Moser, Malene Johanne Petersen, Marianne Hoffmann, Henrik Hasle, Sarah Weischendorff, Klaus Müller   +8 more
wiley   +1 more source

HIV and haematopoiesis [PDF]

, 2019
Human immunodeficiency virus (HIV) infection not only leads to a compromised immune system, but also disrupts normal haematopoiesis, resulting in the frequent manifestation of cytopenias (anaemia, thrombocytopenia and neutropenia).
Khoosal, R, Mellet, J, Nel, J.G, Pepper, M.S, Durandt, C, Potgieter, J.C, Rossouw, T, Herd, C   +7 more
core   +3 more sources

Oxaliplatin-induced haematological toxicity and splenomegaly in mice.

PLoS ONE, 2020
PurposeHaematological toxicities occur in patients receiving oxaliplatin. Mild anaemia (grade 1-2) is a common side effect and approximately 90% of recipients develop measurable spleen enlargement.
Justin G Lees, Daniel White, Brooke A Keating, Mallory E Barkl-Luke, Preet G S Makker, David Goldstein, Gila Moalem-Taylor   +6 more
doaj   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Bone Marrow Fibrosis as a Predictor of Extramedullary Disease in Multiple Myeloma

European Journal of Haematology, EarlyView.
ABSTRACT The correlation between bone marrow fibrosis (BMF) and extramedullary disease has yet to be fully elucidated in patients with newly diagnosed multiple myeloma. Therefore, we aimed to analyze the incidence of BMF in newly diagnosed multiple myeloma patients and evaluate the relationship between BMF and synchronous soft tissue extramedullary ...
Hilal Senkal, Ali Yilmaz Altay, Emine Goknur Isik, Simge Erdem, Metban Mastanzade, Gulcin Yegen, Mustafa Murat Ozbalak, İpek Yonal Hindilerden, Mustafa Nuri Yenerel, Sevgi Kalayoglu Besisik   +9 more
wiley   +1 more source

Making Blood: The Haematopoietic Niche throughout Ontogeny

Stem Cells International, 2015
Approximately one-quarter of all cells in the adult human body are blood cells. The haematopoietic system is therefore massive in scale and requires exquisite regulation to be maintained under homeostatic conditions.
Mohammad A. Al-Drees, Jia Hao Yeo, Badwi B. Boumelhem, Veronica I. Antas, Kurt W. L. Brigden, Chanukya K. Colonne, Stuart T. Fraser   +6 more
doaj   +1 more source

Cutaneous involvement by myeloid leukaemias: challenging cases with important implications

Histopathology, EarlyView.
Myeloid leukaemias and precursors involving the skin are often challenging to diagnose with varied and overlapping clinical and histopathologic features. Nonetheless, they are critical for pathologists to recognize and accurately classify. This review discusses the clinical, histopathological and genetic features of myelodysplasia cutis (A) and ...
Alexandra C. Hristov
wiley   +1 more source