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Extramedullary hematopoiesis in cancer [PDF]

Experimental and Molecular Medicine
Hematopoiesis can occur outside of the bone marrow during inflammatory stress to increase the production of primarily myeloid cells at extramedullary sites; this process is known as extramedullary hematopoiesis (EMH).
Derek A. G. Barisas, Kyunghee Choi
doaj   +6 more sources

Extramedullary hematopoiesis in ribs and severe pulmonary hypertension disease following intermediate beta-thalassemia: a case report [PDF]

Journal of Medical Case Reports, 2023
Background Thalassemia is a type of congenital hemoglobinopathy that falls into the category of hemolytic anemias. Extramedullary hematopoiesis is a complication of this disease, which is a mechanism to compensate for chronic anemia in these patients ...
Ali Hossein Samadi Takaldani, Nima Javanshir, Helia Honardoost, Mohammad Negaresh   +3 more
doaj   +3 more sources

Homeostatic and pathogenic extramedullary hematopoiesis [PDF]

Journal of Blood Medicine, 2010
Chang H KimLaboratory of Immunology and Hematopoiesis, Department of Comparative Pathobiology; Purdue Cancer Center, Purdue University, West Lafayette, IN, USAAbstract: Extramedullary hematopoiesis (EH) is defined as hematopoiesis occurring in organs ...
Chang H Kim
doaj   +8 more sources

Pulmonary Extramedullary Hematopoiesis in a Patient with Chronic Asthma Resembling Lung Cancer: A Case Report [PDF]

Case Reports in Medicine, 2012
Background. Extramedullary hematopoiesis is most often seen in reticuloendothelial organs specially spleen, liver, or lymph nodes, and it is rarely seen in lung parenchyma.
Massood Hosseinzadeh, Navid Omidifar, Perikala Vijayananda Kumar, Alireza Rasekhi   +3 more
doaj   +5 more sources

Paravertebral Mass in a Patient with Hemolytic Anemia: Computed Tomographic Findings [PDF]

Case Reports in Medicine, 2010
Extramedullary hematopoiesis is characterized by the presence of hematopoietic tissue outside of the bone marrow and is typically associated with chronic hemolytic anemias.
Juliana França Carvalho, Edson Marchiori, Gláucia Zanetti, Claudia Mauro Mano, Branca Sarcinelli-Luz, Flávia Gavinho Vianna, Carla Assed, Isabella Guedes Santos, Alair Augusto S. M. D. Santos, Alberto Domingues Vianna   +9 more
doaj   +5 more sources

A case of intrathoracic extramedullary hematopoiesis-associated pleural effusion in a beta-thalassemia intermedia patient and a short literature review [PDF]

SAGE Open Medical Case Reports
Extramedullary hematopoiesis is a phenomenon that occurs in conditions of ineffective bone marrow function. In the context of thalassemias, extramedullary hematopoiesis is more frequently observed in beta-thalassemia intermedia patients, with thoracic ...
Georgios Petros Barakos, Athanasia Papazafiropoulou, Konstantinos Mihos, Valeria Eminidou, Stefani Andronikou, Lemonia Ainalidou, Niki Mofori, Themis Gkraikou, Georgios Athanasakis, Nikolaos Papanas, Stavros Antonopoulos   +10 more
doaj   +2 more sources

Pelvic extramedullary hematopoiesis with life-threatening hemorrhage: a case report [PDF]

International Journal of Emergency Medicine
Background Thalassemia is an inherited blood disorder characterized by defective hemoglobin production, leading to chronic anemia and the necessity for lifelong blood transfusions.
Zainab Habbash, Ali Hassan, Sawsan Kadhem, Nawra Mujbel, Mahdi Aljawad   +4 more
doaj   +2 more sources

A case report of mediastinal extramedullary hematopoiesis: imaging, pathological and thoracoscopic biopsy correlation [PDF]

Journal of Cardiothoracic Surgery
Objective To summarize the clinical features, imaging characteristics, and surgical diagnosis and treatment experience of mediastinal extramedullary hematopoiesis.
Fengbo Yao, Dingbiao Li, Ying Wang, Yanfei Wang, Yongchang Lv   +4 more
doaj   +2 more sources

Acute spinal cord compression in the setting of chronic extramedullary hematopoiesis of the thoracic spine [PDF]

North American Spine Society Journal, 2023
Background: Though rare, pathologic extramedullary hematopoiesis (EMH) can occur in response to myeloproliferative disorders and may present as paravertebral masses.
Ty Agaisse, BS, Cameron Thomson, MD, Mariah Balmaceno-Criss, BS, Leland McCluskey, MD, Bassel G. Diebo, MD, Eren Kuris, MD, Alan H. Daniels, MD   +6 more
doaj   +2 more sources

MCL-1 Inhibitor S63845 Distinctively Affects Intramedullary and Extramedullary Hematopoiesis [PDF]

Pharmaceutics, 2023
Conventional chemotherapy for killing cancer cells using cytotoxic drugs suffers from low selectivity, significant toxicity, and a narrow therapeutic index.
Hexiao Zhang, Fei Li, Ming Yang, Wenshan Zhang, Mei He, Hui Xu, Chaoqun Wang, Yiran Zhang, Wei Wang, Yingdai Gao, Xue Du, Yinghui Li   +11 more
doaj   +2 more sources