Results 101 to 110 of about 14,297 (183)

Extramedullary hematopoiesis presenting as a solitary renal mass and mimicking a malignant tumor: A rare case report

Archives of Medicine and Health Sciences, 2013
Extramedullary hematopoiesis (EMH) is the development of hematopoietic tissue outside the bone marrow and it most often occurs in the liver and spleen. Renal EMH is quite rare, and there are very few case reports concerning the kidney. We describe a case
Basharat Mubeen, Iqbal M Lone, Arif Hameed, Annu Charak, Imza Feroz   +4 more
doaj   +1 more source

Unicentric mixed variant castleman disease associated with intrabronchial plasmacytoma. [PDF]

, 2014
Castleman disease (CD), described as a heterogeneous lymphoproliferative disorder, can be divided into different subtypes according to clinical appearance (unicentric and multicentric form) and histopathological features (hyaline vascular, plasma cell ...
A Carbone, A Slotwiner, AR Keller, Attila Csekeő, B Castleman, BT Lin, D El Demellawy, DC Schlosnagle, DM Menke, DM Menke, DMP Cronin, ED Hsi, G Frizzera, Gergely Varga, GM Dores, György Balázs, György Losonczy, JB Arlet, Judit Csomor, K Nagai, K Yoshizaki, L Zhang, Lilla Tamási, M Chilosi, M Hakozaki, MQ Du, N Tsukamoto, Noémi Eszes, PA Hall, PG Murray, R Burger, S Curioni, S Wilkinson, SJ Brandt, T Radaszkiewicz, T Shuaipaj, T Terada, TW Muskardin, Veronika Müller, WB Bowne, X Sun, Y Aoki, Ágota Szepesi   +42 more
core   +1 more source

NPM1 and IDH1/2 Mutations Show Limited Prognostic Impact in Relapsed/Refractory AML: Evidence From the AVALON Cohort

Hematological Oncology, Volume 44, Issue 1, January 2026.
ABSTRACT In the AVALON cohort of relapsed/refractory AML treated with venetoclax plus hypomethylating agents, NPM1 and IDH1/2 mutations showed no significant impact on response or survival. These findings indicate that prognostic models for relapsed AML should consider treatment context rather than baseline mutation status.
Calogero Vetro, Irene Azzali, Elisabetta Petracci, Cristina Papayannidis, Eleonora Eleuteri, Fanny Erika Palumbo, Vincenzo Federico, Nicola Fracchiolla, Patrizia Zappasodi, Maria Paola Martelli, Maria Benedetta Giannini, Lorenzo Brunetti, Raffaele Palmieri, Jacopo Nanni, Giorgia Simonetti, Fabio Guolo, Paola Minetto, Luca Maurillo, Federica Gigli, Atto Billio, Elisabetta Todisco, Giovanni Martinelli, Giovanni Marconi   +22 more
wiley   +1 more source

Elranatamab Exposure–Safety Analysis in Relapsed or Refractory Multiple Myeloma

The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Elranatamab, a bispecific antibody targeting B‐cell maturation antigen, is approved for the treatment of relapsed or refractory multiple myeloma (RRMM). An exposure–safety analysis was conducted using the data from patients with RRMM across four clinical studies, MagnetisMM‐1, 2, 3, and 9 (NCT03269136, NCT04798586, NCT04649359, and NCT05014412)
Pooneh Soltantabar, Jennifer Hibma, Diane Wang, Umberto Conte, Anne Hickman, Mohamed Elmeliegy   +5 more
wiley   +1 more source

Safety Assessment of Repeated Oral Administration of Tolfenamic Acid in Japanese Quails: Haematological, Biochemical and Histopathological Evaluations

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
Safety of tolfenamic acid in Japanese quails. ABSTRACT Objective This study evaluated the safety profile of tolfenamic acid following repeated oral administration in Japanese quails (Coturnix coturnix japonica) at doses of 2 and 8 mg/kg every 12 h for 7 days. Methods The 42 quails were randomly assigned to three groups. The first group (n = 6) received
Fatih Hatipoglu, Ayday Cunusova, Nariste Kadiraliyeva, Nur Abdimanap Uulu, Burak Mete, Orhan Corum, Kamil Uney   +6 more
wiley   +1 more source

Hedgehogs and Angiostrongylus cantonensis: Uncovering the Role of Atelerix albiventris in the Parasite Life Cycle

Integrative Zoology, Volume 21, Issue 1, Page 104-115, January 2026.
ABSTRACT The ongoing invasion of the zoonotic parasite Angiostrongylus cantonensis threatens humans, other mammals, and birds. In Mallorca, neurological disorders associated with this parasite are increasingly reported in free‐living Algerian hedgehogs, Atelerix algirus, raising public health concerns.
Anna Šipková, Kristýna Javorská, Lucia Anettová, Divakaran Pandian, Petr Cibulka, Jana Kačmaříková, Ladislav Novotný, David Modrý   +7 more
wiley   +1 more source

Video-assisted thoracoscopic surgery for intrathoracic extramedullary hematopoiesis

Journal of Minimal Access Surgery, 2007
Extramedullary hematopoiesis is a rare cause of an intrathoracic mass in individuals with hemolytic disorders. It can be clinically confused with other tumors of the mediastinum.
Giblin E, Frankel K, Mortman K
doaj  

Efficacy of Momelotinib in Myelofibrosis Patients: Results From a Multicenter Study

European Journal of Haematology, Volume 116, Issue 1, Page 23-30, January 2026.
ABSTRACT Momelotinib, a novel JAK1/2 inhibitor with inhibitory activities on activin A receptor type I, has shown breakthrough clinical efficacy in patients with myelofibrosis (MF) and anemia, a disease‐related manifestation of challenging management. In this retrospective real‐life multicenter Italian study, we investigated the safety and efficacy of ...
Maria Carmen Martorelli, Novella Pugliese, Maria Di Perna, Danilo De Novellis, Assunta Lombardi, Laura De Fazio, Giuseppina Loglisci, Ilaria Peluso, Matteo Molica, Carolina Copia, Alessandra Ricco, Antonella Bruzzese, Francesco Mendicino, Vincenza De Fazio, Teresa Maria Santeramo, Rosario Bianco, Giuseppe Monaco, Raffaele Fontana, Roberto Guariglia, Bianca Serio, Serena Luponio, Anna Maria Della Corte, Antonella Malandrini, Valentina Giudice, Ferdinando Frigeri, Giuseppe Tarantini, Attilio Guarini, Massimo Gentile, Pellegrino Musto, Mario Annunziata, Nicola Di Renzo, Marco Rossi, Catello Califano, Fabrizio Pane, Carmine Selleri   +34 more
wiley   +1 more source

Clonal Progression and Leukemic Transformation of a TP53 Mutated Post‐Polycythaemia Vera Myelofibrosis

European Journal of Haematology, Volume 116, Issue 1, Page 93-97, January 2026.
ABSTRACT Previous studies investigating the role of TP53 mutations in chronic phase MPN have yielded inconsistent results. As such, the clinical relevance of these mutations remains to be elucidated. We report a case of a 67‐year‐old woman with a leukemic transformation of a post‐polycythaemia vera myelofibrosis (post‐PV MF) that culminated in the rare
Isidor Minović, Bart Koopman, Joris J. W. Ploegmakers, Elise M. J. van der Logt, Arjen H. G. Cleven, Anouk van der Veen, Arjan Buijs, André B. Mulder, Emanuele Ammatuna   +8 more
wiley   +1 more source

Research opportunities in loss of red blood cell mass in space flight [PDF]

Decreases of red blood cell mass and plasma volume have been observed consistently following manned space flights. Losses of red cell mass by United States astronauts have averaged 10 to 15% (range: 2 to 21%).
Fisher, K. D., Talbot, J. M.
core   +1 more source