Thalassemia, extramedullary hematopoiesis, and spinal cord compression: A case report
Surgical neurology international, 2016 Background: Extramedullary hematopoiesis (EMH) refers to hematopoiesis outside of the medulla of the bone. Chronic anemia states such as thalassemia can cause hematopoietic tissue to expand in certain locations.
Syed Sarmad Bukhari +2 more
semanticscholar +1 more source
Unraveling a Rare Case of Epidural Extramedullary Hematopoiesis in a Patient With Transfusion-Dependent Beta Thalassemia Presenting With Spinal Cord Compression. [PDF]
CureusMasalma R +9 more
europepmc +3 more sources
American Journal of Hematology, Volume 100, Issue S4, Page 5-15, June 2025.ABSTRACT With the recent publication of new classification systems of hematopoietic neoplasms, understanding how recognition of disease entities has occurred over time and the subsequent development of formal disease classifications is of importance. This review focuses on the early recognition of myeloid disorders, especially chronic myeloid disorders,
Daniel A. Arber, Attilio Orazi
wiley +1 more source
Gene expression and functional annotation of the human and mouse choroid plexus epithelium [PDF]
, 2013 Background: The choroid plexus epithelium (CPE) is a lobed neuro-epithelial structure that forms the outer blood-brain barrier. The CPE protrudes into the brain ventricles and produces the cerebrospinal fluid (CSF), which is crucial for brain homeostasis.
Bergen, A.A.B. (Arthur) +7 more
core +1 more source
The disruption of hematopoiesis in tumor progression
Blood Science, 2019 . Human adult hematopoiesis maintains homeostasis by replacing depleted progeny pools and inducing a primary immune response to infectious diseases and tumors.
Xiaofang Wang, Yangqiu Li
doaj +1 more source
Targeted Therapies in Myelofibrosis: Present Landscape, Ongoing Studies, and Future Perspectives
American Journal of Hematology, Volume 100, Issue S4, Page 30-50, June 2025.ABSTRACT Myelofibrosis (MF) is a myeloproliferative neoplasm that is accompanied by driver JAK2, CALR, or MPL mutations in more than 90% of cases, leading to constitutive activation of the JAK–STAT pathway. MF is a multifaceted disease characterized by trilineage myeloid proliferation with prominent megakaryocyte atypia and bone marrow fibrosis, as ...
Giuseppe G. Loscocco, Paola Guglielmelli
wiley +1 more source
Chronic Idiopathic Myelofibrosis Presenting as Cauda Equina Compression due to Extramedullary Hematopoiesis: A Case Report [PDF]
, 2007 Extramedullary hematopoiesis (EMH) is occasionally reported in idiopathic myelofibrosis and is generally found in the liver, spleen, and lymph nodes several years after diagnosis.
Close +19 more
core +2 more sources
Myelopathy due to Spinal Extramedullary Hematopoiesis in a Patient with Polycythemia Vera
Case Reports in Orthopedics, 2017 Extramedullary hematopoiesis (EMH) occasionally occurs in patients exhibiting hematological disorders with decreased hematopoietic efficacy. EMH is rarely observed in the spinal epidural space and patients are usually asymptomatic.
Shuhei Ito +10 more
semanticscholar +1 more source
American Journal of Hematology, Volume 100, Issue S4, Page 16-29, June 2025.ABSTRACT Allogeneic hematopoietic stem‐cell transplantation (HCT) remains the only potentially curative therapy for patients with myelodysplastic neoplasms (MDS) and myelofibrosis (MF) and is the standard care for eligible patients with higher‐risk disease. Despite significant advancements, both diseases pose unique challenges due to their clinical and
Nico Gagelmann, Nicolaus Kröger
wiley +1 more source
A case of perirenal extramedullary hematopoiesis in a patient with primary myelofibrosis
CEN Case Reports, 2017 Extramedullary hematopoiesis (EMH) is hematopoiesis in organs outside the bone marrow and most frequently occurs in the liver, spleen, and lymph nodes.
K. Imai +5 more
semanticscholar +1 more source