Results 31 to 40 of about 14,297 (183)
Extramedullary Hematopoiesis Generates Ly-6C(high) Monocytes That Infiltrate Atherosclerotic Lesions [PDF]
, 2012 BACKGROUND: Atherosclerotic lesions are believed to grow via the recruitment of bone marrow-derived monocytes. Among the known murine monocyte subsets, Ly-6C(high) monocytes are inflammatory, accumulate in lesions preferentially, and differentiate.
Chudnovskiy, A. +15 more
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Case Reports in Medicine, 2012 Background. Extramedullary hematopoiesis is most often seen in reticuloendothelial organs specially spleen, liver, or lymph nodes, and it is rarely seen in lung parenchyma.
Massood Hosseinzadeh +3 more
doaj +1 more source
Journal of Medical Case Reports, 2011 Introduction Extramedullary hematopoiesis occurs in approximately 15% of cases of thalassemia. Intracranial deposits of extramedullary hematopoiesis are an extremely rare compensatory process in intermediate and severe thalassemia.
Tabesh Homayoun +5 more
doaj +1 more source
MCL-1 Inhibitor S63845 Distinctively Affects Intramedullary and Extramedullary Hematopoiesis
Pharmaceutics, 2023 Conventional chemotherapy for killing cancer cells using cytotoxic drugs suffers from low selectivity, significant toxicity, and a narrow therapeutic index.
Hexiao Zhang +11 more
doaj +1 more source
Studies on reticuloendothelial system and hematopoiesis. II. A study on the morphology and function of erythroblastic islet [PDF]
, 1965 1. For the purpose to clarify the role of reticuloendothelial cells in the center of erythroblastic islet, the medullary and extramedullary erythropoietic foci in convalescence of phenylhydrazine arternia were observed by light and electron microscopies,
Matsuoka, Kenichi
core +1 more source
Inositol phosphatase SHIP1 is a primary target of miR-155 [PDF]
, 2009 MicroRNA-155 (miR-155) has emerged as a critical regulator of immune cell development, function, and disease. However, the mechanistic basis for its impact on the hematopoietic system remains largely unresolved.
Baltimore, David +3 more
core +3 more sources
Paravertebral Mass in a Patient with Hemolytic Anemia: Computed Tomographic Findings
Case Reports in Medicine, 2010 Extramedullary hematopoiesis is characterized by the presence of hematopoietic tissue outside of the bone marrow and is typically associated with chronic hemolytic anemias.
Juliana França Carvalho +9 more
doaj +1 more source
Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder [PDF]
, 2008 Mammalian microRNAs are emerging as key regulators of the development and function of the immune system. Here, we report a strong but transient induction of miR-155 in mouse bone marrow after injection of bacterial lipopolysaccharide (LPS) correlated ...
Baltimore, David +7 more
core +3 more sources
Hematopoietic-restricted Ptpn11E76K reveals indolent MPN progression in mice [PDF]
, 2018 Juvenile Myelomonocytic Leukemia (JMML) is a pediatric myeloproliferative neoplasm (MPN) that has a poor prognosis. Somatic mutations in Ptpn11 are the most frequent cause of JMML and they commonly occur in utero.
Chan, Rebecca J. +4 more
core +1 more source
Osteopetrosis: a rare case of portal hypertension
Future Science OA, 2022 Osteopetrosis is a rare genetic bone disorder characterized by a defect in osteoclasts recruitment and function. Its manifestations are numerous and they mainly include skeletal and dental deformities, cranial nerve entrapment and infections.
Amal Khsiba +7 more
doaj +1 more source