Results 51 to 60 of about 69,180 (314)
Journal of Pediatric Surgery Case Reports, 2022 Extramedullary hematopoiesis occurs in the setting of hematologic disorders or malignancies when the activity of the bone marrow is insufficient to generate blood cells.
Janet Rae Julson +3 more
doaj
Inositol phosphatase SHIP1 is a primary target of miR-155 [PDF]
, 2009 MicroRNA-155 (miR-155) has emerged as a critical regulator of immune cell development, function, and disease. However, the mechanistic basis for its impact on the hematopoietic system remains largely unresolved.
Baltimore, David +3 more
core +3 more sources
Gaucher Disease and Myelofibrosis: A Combined Disease or a Misdiagnosis? [PDF]
, 2018 Background: Gaucher disease (GD) and primary myelofibrosis (PMF) share similar clinical and laboratory features, such as cytopenia, hepatosplenomegaly, and marrow fibrosis, often resulting in a misdiagnosis.
Cardarelli, L +5 more
core +1 more source
Multi-Agent Systems and Blood Cell Formation [PDF]
Multi-Agent Systems - Modeling, Interactions, Simulations and Case
Studies, InTech (Ed.) (2011) 502, 2013 The objective of this chapter is to give an insight of the mathematical modellng of hematopoiesis using multi-agent systems. Several questions may arise then: what is hematopoiesis and why is it interesting to study this problem from a mathematical point of view? Has the multi-agent system approach been the only attempt done until now?
arxiv +1 more source
Master regulators as order parameters of gene expression states [PDF]
Phys. Rev. E 103, 012409 (2021), 2020 Cell type-specific gene expression patterns are represented as memory states of a Hopfield neural network model. It is shown that order parameters of this model can be interpreted as concentrations of master transcription regulators that form concurrent positive feedback loops with a large number of downstream regulated genes.
arxiv +1 more source
Journal of Medical Case Reports, 2011 Introduction Extramedullary hematopoiesis occurs in approximately 15% of cases of thalassemia. Intracranial deposits of extramedullary hematopoiesis are an extremely rare compensatory process in intermediate and severe thalassemia.
Tabesh Homayoun +5 more
doaj +1 more source
Extramedullary hematopoiesis in renal allograft [PDF]
Clinical Kidney Journal, 2013 Extramedullary hematopoiesis (EMH), defined as the presence of hematopoietic elements outside of the medullary cavity of bone, has been reported in patients with various hematopoietic neoplasms including myelofibrosis. EMH commonly occurs in the liver and spleen (resulting in hepatosplenomegaly) and uncommonly involves the kidney.
Guilan Chen +4 more
openaire +3 more sources
On the existence and exponential attractivity of a unique positive almost periodic solution to an impulsive hematopoiesis model with delays [PDF]
Acta Math Vietnam 41 (2016) 337-354, 2015 In this paper, a generalized model of hematopoiesis with delays and impulses is considered. By employing the contraction mapping principle and a novel type of impulsive delay inequality, we prove the existence of a unique positive almost periodic solution of the model.
arxiv +1 more source
Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder [PDF]
, 2008 Mammalian microRNAs are emerging as key regulators of the development and function of the immune system. Here, we report a strong but transient induction of miR-155 in mouse bone marrow after injection of bacterial lipopolysaccharide (LPS) correlated ...
Baltimore, David +7 more
core +3 more sources
Extramedullary Hematopoiesis Generates Ly-6C(high) Monocytes That Infiltrate Atherosclerotic Lesions [PDF]
, 2012 BACKGROUND: Atherosclerotic lesions are believed to grow via the recruitment of bone marrow-derived monocytes. Among the known murine monocyte subsets, Ly-6C(high) monocytes are inflammatory, accumulate in lesions preferentially, and differentiate.
Chudnovskiy, A. +15 more
core +1 more source