A 54-Year-Old Woman with Myelofibrosis and Massive Hemothorax Due to Primary Extramedullary Hematopoiesis of the Pleura [PDF]
Extramedullary hematopoiesis, which represents ectopic blood cell production, is usually an incidental finding accompanying hematologic pathology. The liver and spleen are the most common sites of extramedullary hematopoiesis, but thoracic involvement is
Agarwal, Anup+5 more
core +3 more sources
A mathematical study of the hematopoiesis process with applications to chronic myelogenous leukemia [PDF]
This paper is devoted to the analysis of a mathematical model of blood cells production in the bone marrow (hematopoiesis). The model is a system of two age-structured partial differential equations. Integrating these equations over the age, we obtain a system of two nonlinear differential equations with distributed time delay corresponding to the cell
arxiv +1 more source
Modelling hematopoiesis mediated by growth factors with applications to periodic hematological diseases [PDF]
Hematopoiesis is a complex biological process that leads to the production and regulation of blood cells. It is based upon differentiation of stem cells under the action of growth factors. A mathematical approach of this process is proposed to carry out explanation on some blood diseases, characterized by oscillations in circulating blood cells.
arxiv +1 more source
Chemotactic Cues for NOTCH1-Dependent Leukemia [PDF]
The NOTCH signaling pathway is a conserved signaling cascade that regulates many aspects of development and homeostasis in multiple organ systems.
Amadori, Alberto+3 more
core +1 more source
Stability Analysis of a Simplified Yet Complete Model for Chronic Myelegenous Leukemia [PDF]
We analyze the asymptotic behavior of a partial differential equation (PDE) model for hematopoiesis. This PDE model is derived from the original agent-based model formulated by (Roeder et al., Nat. Med., 2006), and it describes the progression of blood cell development from the stem cell to the terminally differentiated state.
arxiv +1 more source
Osteopetrosis: a rare case of portal hypertension
Osteopetrosis is a rare genetic bone disorder characterized by a defect in osteoclasts recruitment and function. Its manifestations are numerous and they mainly include skeletal and dental deformities, cranial nerve entrapment and infections.
Amal Khsiba+7 more
doaj +1 more source
From EMT to HSC to AML: ZEB2 is a cell fate switch. [PDF]
In this issue of Blood, complimentary studies by J. Li et al1 and H. Li et al2 identify the transcription factor ZEB2 as a critical regulator of multilineage differentiation in both normal and malignant hematopoiesis.
Meyer, Sara E.
core +2 more sources
Liver metastasis of breast carcinoma: An unusual presentation and growth pattern
Breast carcinoma is one of the tumors that frequently metastasize to the liver. Extramedullary hematopoiesis (EMH) usually occurs due to insufficient medullary hematopoiesis.
Mine Özşen+3 more
doaj +1 more source
An 80-year-old woman with myelofibrosis and diffuse mosaic attenuation on chest computed tomography
An 80-year-old woman with myelofibrosis sought evaluation for progressive dyspnea. Her past medical history included essential thrombocytosis, which transformed to myelofibrosis.
Harpreet Singh+4 more
doaj
Studies on reticuloendothelial system and hematopoiesis. II. A study on the morphology and function of erythroblastic islet [PDF]
1. For the purpose to clarify the role of reticuloendothelial cells in the center of erythroblastic islet, the medullary and extramedullary erythropoietic foci in convalescence of phenylhydrazine arternia were observed by light and electron microscopies,
Matsuoka, Kenichi
core +1 more source