Results 81 to 90 of about 14,297 (183)

Renal Bleeding Due to Extramedullary Hematopoiesis in a Patient With Chronic Myelogenous Leukemia

Urology Case Reports, 2014
Chronic myelogenous leukemia (CML) is a myeloproliferative disorder that normally presents in middle-aged adults. Renal infiltration and extramedullary hematopoiesis in renal tissue has been rarely reported.
Stephanie Zettner, Sandeep G. Mistry
doaj   +1 more source

Alleviation of acute radiation-induced bone marrow failure in mice with human fetal placental stromal cell therapy

Stem Cell Research & Therapy, 2020
Purpose Selected placental mesenchymal stromal cells isolated from the fetal mesenchymal placental tissues (f-hPSCs) were tested as cell therapy of lethal acute radiation syndrome (ARS) with bone marrow regeneration and induced extramedullary ...
Evgenia Volinsky, Astar Lazmi-Hailu, Nerel Cohen, Boaz Adani, Mohammad Faroja, Myriam Grunewald, Raphael Gorodetsky   +6 more
doaj   +1 more source

Clonal Evolution and Lineage Switch from T‐Cell Acute Lymphoblastic Leukemia to Acute Myeloid Leukemia in Therapy‐Resistant PICALM::MLLT10 Leukemia

eJHaem, Volume 7, Issue 1, February 2026.
ABSTRACT Background PICALM::MLLT10‐positive T‐ALL is rare and associated with poor prognosis. Lineage switch to AML is exceptionally uncommon, particularly after long‐term remission. Case Presentation We report an adolescent PICALM::MLLT10‐positive T‐ALL with a cortical thymocyte, non‐ETP phenotype.
Machiko Kawamura, Daichi Sadato, Masayuki Haruta, Nobuko Kubota, Yuka Harada, Takeshi Kobayashi, Noriko Doki, Fumio Kasai, Yu Nishimura, Hirofumi Kobayashi, Nobuo Maseki   +10 more
wiley   +1 more source

Sepsis secondary to cystitis in a guinea pig (Cavia porcellus)

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract Cystitis is a frequent, often chronic and recurrent disease in guinea pigs (Cavia porcellus). This report describes a case of a 2‐year‐old, entire, female Abyssinian guinea pig with fatal cystitis. The animal was presented with progressive chronic cystitis and had previously been treated with several antibiotics and analgesics.
Anika Mische, Katharina Landmann, Lars Mundhenk, Antina Lübke‐Becker, Kerstin Müller   +4 more
wiley   +1 more source

Non-Transfusion-Dependent Thalassemia: An Update on Complications and Management [PDF]

, 2018
Patients with non-transfusion-dependent thalassemia (NTDT) experience many clinical complications despite their independence from frequent transfusions.
Bou-Fakhredin, Rayan, Cappellini, Maria Domenica, Saliba, Antoine N., Sleiman, Joseph, Taher, Ali T., Tarhini, Ali   +5 more
core   +4 more sources

Oral mucosal manifestations with identical mutations to the bone marrow in a patient with VEXAS syndrome

Rheumatology &Autoimmunity, EarlyView.
Lilian Vasaitis, Lena Blomstrand, Tatjana Pandzic, Miklos Gulyas, Panagiotis Baliakas, Viktor Ljungström   +5 more
wiley   +1 more source

Lymphoid Organs Remodeling in Non‐Obese Diabetic Goto‐Kakizaki Rats Immunized With SARS‐CoV‐2 Antigens

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
The Goto‐Kakizaki rat, a non‐obese model of type 2 diabetes mellitus (T2DM), exhibits lymphoid organ remodeling, including baseline thymic involution and splenic white pulp reorganization. Following completion of a three‐dose SARS CoV‐2 antigen immunization protocol, anti‐Spike IgG levels were significantly increased despite these structural changes ...
Sara Araujo Pereira, Mariana Cruz Lazzarin, Maria Lucia Zaidan Dagli, Bianca de Carvalho Lins Fernandes Távora, Eliana Faquim de Lima Mauro, Marcelo Larami Santoro, Sandra Coccuzzo Sampaio Vessoni, Luis Roberto de Camargo Gonçalves, Marina Sakamoto Sotoyama, Ricardo das Neves Oliveira, Vania Gomes de Moura Mattaraia, Rui Curi   +11 more
wiley   +1 more source

Bifurcate Regulation of Hematopoietic Homeostasis and Bone Osteogenesis by VHL‐HIF2α‐Controlled Adipocyte Function

Advanced Science, Volume 13, Issue 5, 27 January 2026.
The VHL‐HIF2α (VHL is Von Hippel‐Lindau) axis in adipocytes differentially regulates hematopoiesis and bone formation through stem cell factor (SCF) and chemerin, respectively. This hypoxia‐responsive pathway in adipocytes establishes a systemic signaling network with HSCs and MSCs to maintain tissue homeostasis, revealing a targetable axis for ...
Qian Li, Jia Li, Anshu Tang, Cong Li, Chao Zhang, Congcong Zhang, Yun‐Cai Liu   +6 more
wiley   +1 more source

The disruption of hematopoiesis in tumor progression

Blood Science, 2019
. Human adult hematopoiesis maintains homeostasis by replacing depleted progeny pools and inducing a primary immune response to infectious diseases and tumors.
Xiaofang Wang, Yangqiu Li
doaj   +1 more source

DNA methyltransferases and their roles in tumorigenesis [PDF]

, 2017
DNA methylation plays an important role in gene expression, chromatin stability, and genetic imprinting. In mammals, DNA methylation patterns are written and regulated by DNA methyltransferases (DNMTs), including DNMT1, DNMT3A and DNMT3B. Recent emerging
Jie Xu, Wu Zhang
core   +1 more source