Results 31 to 40 of about 1,690 (152)

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

Green swans and blue skies: Climate change and insolvency risk for financial institutions

International Insolvency Review, EarlyView.
Abstract This lecture in honour of the late Gabriel Moss QC and Ian Fletcher QC examines the challenge of climate‐related financial risk. Prudential regulators and central banks recognize that the systemic nature of climate‐related financial risk makes it an emerging vulnerability relevant to cross‐border insolvency resolution.
Janis Sarra
wiley   +1 more source

Hidden Costs of Ethical Fashion: Sustainable Development Goals and Garment Worker Exploitation in Bangladesh

Sustainable Development, EarlyView.
ABSTRACT Across garment factories in the Global South, the promise of “ethical fashion” coexists with poverty wages and retaliation. This study examines why the global call for decent work has not improved labor conditions in Bangladesh's ready‐made garment industry.
Md. Rafiqul Islam Rana
wiley   +1 more source

Analogies and differences between the logic behind statistical hypothesis testing and proofs by contradiction: What can we learn from them?

Teaching Statistics, EarlyView.
Abstract Statistical hypothesis testing (SHT) is widely employed across numerous scientific disciplines, and a clear understanding of its underlying logic is essential for the broader scientific community. Here, drawing upon both epistemological and statistical perspectives, we aim to clarify—primarily for educational purposes—the logical relationship ...
Maria Cristina Amoretti, Daniele De Martini   +1 more
wiley   +1 more source

Different Frontier, Same Legal Script? On the Course of Replicating Earth's Patterns in Space

The Modern Law Review, EarlyView.
As states and private actors expand their activities in outer space, the international legal framework governing this domain risks extending longstanding structures of global inequality beyond Earth. This article examines how international space law, shaped by a broader disciplinary pattern of reactive legal development, is poised to reproduce ...
Sivan Shlomo‐Agon, Michal Saliternik
wiley   +1 more source

Exemplary Damages as Public Interest Damages: Implications for Rights of Action, Settlement and the Distribution of Awards

The Modern Law Review, EarlyView.
Exemplary damages are commonly understood as public interest awards. This article explores the logical implications of understanding them in this way for a tort claimant's rights of action and settlement, and for the proper distribution of awards. One implication, it suggests, is that settlements, being compromises of public ends, should require court ...
Kit Barker
wiley   +1 more source

THE VIOLENCE OF FULL COST RECOVERY: Financing Water Infrastructure, and the History and Future of Perpetual Crisis in Mombasa

International Journal of Urban and Regional Research, EarlyView.
Abstract Foregrounding the role of finance, this article examines the historical production and future trajectory of the urban water crisis in Mombasa. Drawing on archival research and contemporary fieldwork, it traces how principles of full cost recovery—institutionalized during the colonial period and later reworked through postcolonial ...
Joe Williams
wiley   +1 more source

Methodological Challenges in Studying Wealthy Families

The British Journal of Sociology, EarlyView.
ABSTRACT Studying the wealthy is not easy. This piece provides suggestions for recruitment, interview strategies, and design to gain high‐quality data on wealthy people. It is based on an interview study of 81 US racially‐diverse families with a median net worth of $25 million. First, to gain access to the wealthy, it is key for the researcher to use a
Annette Lareau
wiley   +1 more source

Pseudonyms, Propaganda, and Prints: The Life and Political Caricatures of William Dent, 1782–931

Journal for Eighteenth-Century Studies, EarlyView.
Abstract ‘Dent was probably an amateur and nothing is known of his life’, state Bryant and Heneage. Despite contributing to caricature's ‘golden age’, William Dent remains overlooked compared to contemporaries like James Gillray. Dent's extensive portfolio (1782–93) and rumoured role as a Pittite propagandist have not secured his place in the canon of ...
Callum D. Smith
wiley   +1 more source

The Unintended Effects of US Regulations on the Value of Cash Holdings of Non‐US Companies: Evidence from the Public Company Accounting Oversight Board's International Inspection Access

Abacus, EarlyView.
We investigate the effects of the Public Company Accounting Oversight Board's (PCAOB) international inspection access on the value of cash holdings for non‐US companies. Utilizing a difference‐in‐differences (DiD) research design, we find that investors assign significantly higher value to a non‐US company's cash holdings when the company's non‐US ...
Hsiao‐Tang Hsu, Huichi Huang, Yutao Li
wiley   +1 more source