Results 101 to 110 of about 106,766 (203)

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

Interdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang, Meng‐Yao Li, Wenlong Sun   +6 more
wiley   +1 more source

LA UNIFICACIÓN DE JURISPRUDENCIA PRETENDIDA POR EL RECURSO EXTRAORDINARIO: VENTAJAS Y PROBLEMAS THE UNIFICATION OF JURISPRUDENCE ALLEGED BY AN EXTRAORDINARY REMEDY: ADVANTAGES AND PROBLEMS

Revista de Derecho (Coquimbo), 2011
El proyecto de Código Procesal Civil en actual tramitación en el Congreso Nacional de Chile incluye una singular innovación en el ámbito recursivo. Se trata del recurso extraordinario, cuya finalidad es, en esencia, unificar la jurisprudencia en materia ...
Jordi Delgado Castro, L. Iván Díaz García   +1 more
doaj  

Book Review: Hinde on Commercial Leases [PDF]

, 2012
This article reviews the book: “Hinde on Commercial Leases”, by G.W ...
Liao, Zhixiong
core   +1 more source

Microelectromechanical system‐based devices for the diagnosis, treatment, and monitoring of ophthalmic diseases

Interdisciplinary Medicine, EarlyView.
Due to the characteristics of miniaturization, high sensing performance, integration, and high comfort, MEMS‐based devices were employed to design sensors, imaging systems, drug delivery systems, retinal prosthesis, surgical tools, and wearable products for the ophthalmic disease diagnosis, treatment, and monitoring.
Yaling Peng, Xiaoming Huang, Xueyuan Zhang, Yiling Jiang, Xin Zhang, Xueying Zeng, Fengyuan Sun, Peng Liu, Jin Zhou, Zewei Luo, Tong Wu   +10 more
wiley   +1 more source

On the Transformative Nature of Luxury Consumption and Consumer Well‐Being: A Systematic Literature Review and Research Agenda

Psychology &Marketing, EarlyView.
ABSTRACT Consuming luxury products and services has received little systematic attention as a potential pathway to consumer well‐being, despite sporadic evidence suggesting that luxury experiences may catalyse self‐transformational processes and happiness‐related outcomes.
Solon Magrizos, Maria C. Voutsa, Minas N. Kastanakis   +2 more
wiley   +1 more source

Case Note: Constitutional Law - Due Process - Municipal Towing Ordinance Authorizing the Assessment of Towing Fees and Storage Charges Without Notice and Opportunity for Hearing Violates Due Process [PDF]

, 1977
Atzori, G., Azzarello, E., Mancuso, S, Marone, E., Redwan, M., Taiti, C.   +5 more
core   +2 more sources

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Meet the Editorial Team. An interview with Amitabha Bandyopadhyay, Assistant Editor, Indian Institute of Technology Kanpur, India

Developmental Dynamics, EarlyView.
Paul Trevorrow, Amitabha Bandyopadhyay
wiley   +1 more source

Coping Behavior in Patients with Parkinson's Disease Prior to Subthalamic Deep Brain Stimulation and Association with Psychiatric Symptoms, Quality of Life and Neuropsychological Status

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Coping behavior of Parkinson's disease (PD) patients undergoing subthalamic Deep Brain Stimulation (STN‐DBS) is poorly understood. Identifying patients with ineffective coping could help prepare them better for surgery. Objectives To clarify coping of PD patients preoperatively and the relation with psychiatric symptoms, quality of ...
Roy Brian Kuiper, Victor Jacobus Geraedts, Niels Anthony van der Gaag, Carel Frederik Ernst Hoffmann, Esther Lauwen, Rodi Zutt, Dirk Adrianus van der Zwart, Hubertus Anthonius Maria Middelkoop, Maria Fiorella Contarino   +8 more
wiley   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano, Giulia Apprato, Serena Francisco, Giuseppe Ermondi, Giulia Caron   +4 more
wiley   +1 more source