Results 211 to 220 of about 150,278 (286)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

Biophysics-based protein language models for protein engineering. [PDF]

open access: yesNat Methods
Gelman S   +7 more
europepmc   +1 more source

Perspective: OLED Displays Singing with the Blues

open access: yesAdvanced Materials, EarlyView.
While blue pixels consume approximately 50% of the energy of OLED display front planes, in the 25 years since their invention, 100% internal efficiency triplet‐controlled phosphorescent OLEDs have not met the stability standards necessary for their adoption.
Stephen R. Forrest   +2 more
wiley   +1 more source

Engineering Free Volume within Frontal Ring‐Opening Metathesis Polymerization via Pendant Plasticization

open access: yesAdvanced Materials, EarlyView.
Norbornene‐based copolymers with tunable n‐alkyl pendant length provide control over matrix free volume, enabling elastomeric materials via frontal ring‐opening metathesis polymerization (FROMP). ABSTRACT Frontal ring‐opening metathesis polymerization (FROMP) enables rapid, energy‐efficient access to high‐performance thermosets and thermoplastics, but ...
Kevin A. Stewart   +4 more
wiley   +1 more source

Superionic Amorphous Li2ZrCl6 and Li2HfCl6

open access: yesAdvanced Materials, EarlyView.
Amorphous Li2HfCl6 and L2ZrCl6 are shown to be promising solid‐state electrolytes with predicted ionic conductivities >20 mS·cm−1. Molecular dynamics simulations with machine‐learning force fields reveal that anion vibrations and flexible MCl6 octahedra soften the Li coordination cage and enhance mobility. Correlation between Li‐ion diffusivity and the
Shukai Yao, De‐en Jiang
wiley   +1 more source

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