Results 51 to 60 of about 58,054 (324)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Exploring supersymmetric wormholes in N $$ \mathcal{N} $$ = 2 SYK with chords

Journal of High Energy Physics, 2023
A feature the N $$ \mathcal{N} $$ = 2 supersymmetric Sachdev-Ye-Kitaev (SYK) model shares with extremal black holes is an exponentially large number of ground states that preserve supersymmetry.
Jan Boruch, Henry W. Lin, Cynthia Yan
doaj   +1 more source

Beurling's criterion and extremal metrics for Fuglede modulus

, 2012
We formulate a necessary and sufficient condition for an admissible metric to be extremal for the Fuglede p-modulus of a system of measures. When p=2, this characterization generalizes Beurling's criterion, a sufficient condition for an admissible metric
Badger, Matthew
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Extremal surfaces in glue-on AdS/ T T ¯ $$ T\overline{T} $$ holography

Journal of High Energy Physics
T T ¯ $$ T\overline{T} $$ deformed CFTs with positive deformation parameter have been proposed to be holographically dual to Einstein gravity in a glue-on AdS3 spacetime [1]. The latter is constructed from AdS3 by gluing a patch of an auxiliary AdS 3 ∗ $$
Luis Apolo, Peng-Xiang Hao, Wen-Xin Lai, Wei Song   +3 more
doaj   +1 more source

Tail Index Estimation of PageRanks in Evolving Random Graphs

Mathematics, 2022
Random graphs are subject to the heterogeneities of the distributions of node indices and their dependence structures. Superstar nodes to which a large proportion of nodes attach in the evolving graphs are considered.
Natalia Markovich, Maksim Ryzhov, Marijus Vaičiulis   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

On the Rotating Charged Black String Solution

, 1993
A rotating charged black string solution in the low energy effective field theory describing five dimensional heterotic string theory is constructed. The solution is labelled by mass, electric charge, axion charge and angular momentum per unit length ...
A. Dabholkar, A. Giveon, A. Giveon, A. Kumar, A. Sen, A. Sen, A. Sen, A. Sen, A. Shapere, C. Callan, C. Callan, C. Nappi, D. Garfinkle, E. Witten, G. Gibbons, G. Gibbons, G. Gibbons, G. Horowitz, G. Horowitz, G. Mandal, G. Veneziano, J. Horne, J. Horne, J. Horne, J. Maharana, J. Maharana, J. Panvel, K. Meissner, M. Duff, M. Duff, M. Gasperini, M. Gasperini, M. Rocek, P. Horava, R. C. Myers, R. C. Myers, S. F. Hassan, S. F. Hassan, S. Giddings, S. Kar, S. Kar, S. Khastgir, S. Khastgir, S. Khastgir, Swapna Mahapatra, T. Busher, T. Busher, V. P. Frolov   +47 more
core   +2 more sources

Harmonic dimension and extremal length [PDF]

Kodai Mathematical Journal, 1994
Let \(R\) be an open Riemann surface with a single boundary component and \(V\) an end of \(R\), that is a relatively noncompact subregion whose relative boundary \(\partial V\) consists of finitely many analytic Jordan curves. Let \({\mathcal P} (V)\) be the class of nonnegative harmonic functions on \(V\) with vanishing boundary values on \(\partial ...
openaire   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source