Results 71 to 80 of about 3,731,733 (343)

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Lengths of extremal square-free ternary words

open access: yesContributions to Discrete Mathematics, 2021
A square-free word $w$ over a fixed alphabet $\Sigma$ is extremal if every word obtained from $w$ by inserting a single letter from $\Sigma$ (at any position) contains a square. Grytczuk et al. recently introduced the concept of extremal square-free word and demonstrated that there are arbitrarily long extremal square-free ternary words.
Lucas Mol, Narad Rampersad
openaire   +3 more sources

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Bounded outdegree and extremal length on discrete Riemann surfaces [PDF]

open access: yes, 2010
Let $T$ be a triangulation of a Riemann surface. We show that the 1-skeleton of $T$ may be oriented so that there is a global bound on the outdegree of the vertices.
William E. Wood
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Extremal length estimates and product regions in Teichm [PDF]

open access: yes, 1994
We study the Teichm\"uller metric on the Teichm\"uller space of a surface of finite type, in regions where the injectivity radius of the surface is small.
Y. Minsky
semanticscholar   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

open access: yesFEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren   +8 more
wiley   +1 more source

Extremal surfaces in glue-on AdS/ T T ¯ $$ T\overline{T} $$ holography

open access: yesJournal of High Energy Physics
T T ¯ $$ T\overline{T} $$ deformed CFTs with positive deformation parameter have been proposed to be holographically dual to Einstein gravity in a glue-on AdS3 spacetime [1]. The latter is constructed from AdS3 by gluing a patch of an auxiliary AdS 3 ∗ $$
Luis Apolo   +3 more
doaj   +1 more source

Fractal properties of particle paths due to generalised uncertainty relations

open access: yesEuropean Physical Journal C: Particles and Fields, 2022
We determine the Hausdorff dimension of a particle path, $$D_\textrm{H}$$ D H , in the recently proposed ‘smeared space’ model of quantum geometry. The model introduces additional degrees of freedom to describe the quantum state of the background and ...
Matthew J. Lake
doaj   +1 more source

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