Results 131 to 140 of about 160 (159)

Unlocking Strength‐Toughness Dilemma in High‐Entropy Borides by Intragranular Microstructural Reconstruction

open access: yesAdvanced Science, EarlyView.
An extreme non‐equilibrium process combining heavy direct current sintering and TiSi2 addition is used to construct intragranular energy dissipation units within high‐entropy boride ceramics to overcome the strength‐toughness trade‐off. The resulting ceramic demonstrates attractive mechanical properties with a flexural strength of 887 MPa and a ...
Yingjun Liu   +13 more
wiley   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

open access: yesAdvanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan   +13 more
wiley   +1 more source

Bridged h‐BN Nanosheets Coatings: Simultaneous Shielding Atomic‐Oxygen Irradiation and Achieving Superior Friction Performance

open access: yesAdvanced Science, EarlyView.
ABSTRACT To confront extreme space environments, a combination of inorganic and organic coatings can provide a pathway for offering highly durable radiation resistance and anti‐friction simultaneously. Herein, a strong interfacial 3D hydrogen‐bonding network is designed to create robust hexagonal boron nitride (h‐BN) based polymer coatings with ...
Zhuoyi Li   +7 more
wiley   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

open access: yesAdvanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio   +6 more
wiley   +1 more source

Interfacial Water Coordination on Ruthenium Oxide Nanoparticles Confined Within Covalent Organic Framework and Its Effect on Electrochemical Nitrate Reduction

open access: yesAdvanced Science, EarlyView.
We demonstrate how oxygen‐deficient ruthenium oxide (RuOx) nanoparticles confined within covalent organic framework achieve highly efficient nitrate‐to‐ammonia conversion. Strong interaction between RuOx nanoparticles and COF results in modified interfacial hydrogen‐bond water network and adsorption of nitrogenous intermediates.
Yun Li   +6 more
wiley   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

open access: yesAdvanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang   +8 more
wiley   +1 more source

Unveiling a Hidden Conversion Pathway in CoSe2 Anodes via Rationally Designed CNT‐Interwoven Hollow Carbon Microclusters for High‐Performance Potassium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
A rational architectural design of hierarchical, CNT‐interwoven hollow carbon microclusters unlocks and stabilizes a unique monoclinic Co3Se4‐mediated conversion–insertion pathway for potassium storage. This structural confinement effectively guides the reaction kinetics and accommodates severe mechanical strain.
Ho Rim Kim   +8 more
wiley   +1 more source

Non‐Equilibrium Synthesis of Whitlockite Assisted by Localized H2O Vapor Pressure

open access: yesAdvanced Science, EarlyView.
A carbon substrate acts as a microheater during intense pulsed light irradiation, enabling rapid heating and cooling for whitlockite formation. In contrast to conventional white ceramic synthesis with weak photothermal response, this platform concentrates thermal energy locally and promotes phase‐selective crystallization under ultrafast ...
Min‐Jung Kim   +5 more
wiley   +1 more source

Causal‐Guided Ultra‐Long‐Term Time Series Forecasting Via Anticipated Covariates

open access: yesAdvanced Science, EarlyView.
Often treated as unknown, information from the future remains underutilized.We demonstrate that in a coupled dynamical system, providing the future state of the effect enables accurate forecasting of the cause for a long timesteps. A time series forecasting paradigm that introduces anticipated covariates to represent such known future states is ...
Jintong Zhao   +4 more
wiley   +1 more source

Fuzzy pairwise extremally disconnected spaces

Fuzzy Sets and Systems, 1998
The concept of fuzzy extremally disconnected spaces, due to \textit{B. Ghosh} [ibid. 46, No. 2, 245-250 (1992; Zbl 0765.54004)] is generalized. A fuzzy bitopological space \((X,\tau_1,\tau_2)\) is said to be: (a) \((\tau_i, \tau_j)\)-fuzzy extremally disconnected \(((\tau_i, \tau_j)\)-FED) if the \(\tau_j\)-closure of every \(\tau_i\)-fo (fuzzy-open ...
Jin-Han Park, Bu Young Lee
openaire   +1 more source

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