This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv +12 more
wiley +1 more source
Fibrosis and inflammatory activity diagnosis of chronic hepatitis C based on extreme learning machine. [PDF]
Cai J, Chen T, Qi Y, Liu S, Chen R.
europepmc +1 more source
A neural network‐enabled permittivity engineering paradigm is introduced, transcending traditional trial‐and‐error design. By decoupling electromagnetic parameters and screening a high‐throughput feature space, an ultrathin (1.0 mm) magnetic absorber is inversely designed, experimentally achieving a superior and customizable 5.1 GHz bandwidth and ...
Chenxi Liu +9 more
wiley +1 more source
Integrating vision transformer-based deep learning model with kernel extreme learning machine for non-invasive diagnosis of neonatal jaundice using biomedical images. [PDF]
Eliazer M +5 more
europepmc +1 more source
A Lattice Genome framework links geometric and process “genes” to lattice “phenotypes” via correction‐calibrated high‐throughput simulations and a growing performance database. Genome‐driven retrieval and recombination of unit cells enables component‐level, regionally tailored multi‐objective design: stress fields are programmed under constant relative
Haoyuan Deng +8 more
wiley +1 more source
Salp Navigation and Competitive based Parrot Optimizer (SNCPO) for efficient extreme learning machine training and global numerical optimization. [PDF]
Adegboye OR +5 more
europepmc +1 more source
2D Metal‐Organic Frameworks for High‐Performance Solid‐State Electrolytes: A Comprehensive Review
In this review, we elucidate the intrinsic advantages, synthetic methodologies, structural characteristics, ion‐transport mechanisms and performance optimization strategies while highlighting representative material systems and applications of 2D MOFs for electrolyte applications.
Changchun Ai +8 more
wiley +1 more source
Method for EEG signal recognition based on multi-domain feature fusion and optimization of multi-kernel extreme learning machine. [PDF]
Guan S, Dong T, Cong LK.
europepmc +1 more source
Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra +6 more
wiley +1 more source
Optimizing Kernel Extreme Learning Machine based on a Enhanced Adaptive Whale Optimization Algorithm for classification task. [PDF]
Lin Z.
europepmc +1 more source

