Results 121 to 130 of about 203,820 (287)

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

open access: yesAdvanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater   +13 more
wiley   +1 more source

Spatiotemporal variations in extreme precipitation and their potential driving factors in non-monsoon regions of China during 1961–2017

open access: yesEnvironmental Research Letters, 2019
Extreme precipitation events affect the ecological environment and are also important for the sustainable development of regional socioeconomics. Although there are some local studies on extreme precipitation events in which the temporal and spatial ...
Zhiyong Ding, Ruijie Lu, Yuyang Wang
doaj   +1 more source

Climate Change Threatens Micronutrient Density of European Winter Wheat

open access: yesAdvanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao   +17 more
wiley   +1 more source

Seasonal and regional variations in extreme precipitation event frequency using CMIP5

open access: yesGeophysical Research Letters, 2016
Understanding how the frequency and intensity of extreme precipitation events are changing is important for regional risk assessments and adaptation planning.
E. Janssen   +3 more
doaj   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang   +7 more
wiley   +1 more source

Analysis for Spatio-temporal Variation Characteristics of Extreme Precipitation in Wanquan River Basin

open access: yesRenmin Zhujiang, 2021
Based on the long-sequence precipitation data of 22 rainfall stations,this paper selects eight extreme precipitation indexes to analyze the temporal evolution and spatial distribution of extreme precipitation in Wanquan River Basin by linear trend method,
XIAO Jing, ZHANG Lu, LIN Youwen
doaj  

Sensitivity of a high‐elevation rocky mountain watershed to altered climate and CO2 [PDF]

open access: yes, 2000
We explored the hydrologic and ecological responses of a headwater mountain catchment, Loch Vale watershed, to climate change and doubling of atmospheric CO2 scenarios using the Regional Hydro‐Ecological Simulation System (RHESSys).
Band, L. E.   +3 more
core   +2 more sources

Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement

open access: yesAdvanced Science, EarlyView.
The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang   +7 more
wiley   +1 more source

Interannual Variability and Trends in Extreme Precipitation in Dronning Maud Land, East Antarctica

open access: yesRemote Sensing
This study examines the trends and interannual variability of extreme precipitation in Antarctica, using six decades (1963–2023) of daily precipitation data from Russia’s Novolazarevskaya Station in East Antarctica. The results reveal declining trends in
Lejiang Yu   +4 more
doaj   +1 more source

The Drought Monitor [PDF]

open access: yes, 2002
There is a need for improved drought monitoring and assessment methods in the United States. Drought is the most costly natural disaster [Federal Emergency Management Agancy (FEMA 1995; Wilhite 2000)], but it is often neglected by developers of ...
Angel, Jim   +11 more
core   +1 more source

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