Results 191 to 200 of about 4,766,593 (246)

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

open access: yesAdvanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang   +9 more
wiley   +1 more source

Soil pH Amelioration Synergizes Carbon Accrual with Yield Gains Under Organic Substitution

open access: yesAdvanced Science, EarlyView.
Soil pH shifts towards neutrality in both acidic and alkaline soils under organic substitution. A global synthesis links pH amelioration to soil organic carbon accrual through enhanced microbial biomass after accounting for added organic carbon and its interaction with pH. This pH amelioration‐shared soil organic carbon accrual accounts for 5.1–8.6% of
Xunzhuo Dong   +7 more
wiley   +1 more source

Biodiversity effects under climate extremes intensify with aridity in grasslands but not forests. [PDF]

open access: yesNat Ecol Evol
Sasaki T   +76 more
europepmc   +1 more source

Dual Randomness From Spatial and Temporal Variations in Stochastic Zinc Gallate Nanoclusters for PUF and TRNG Co‐Driven Image Generation

open access: yesAdvanced Science, EarlyView.
A dual‐randomness hardware platform is demonstrated by integrating PUF and TRNG functionalities into mixed‐ZGO nanoclusters. By leveraging spatial and temporal stochasticity, the mixed‐ZGO NCs device enables both unique identification and random signal generation.
Seungme Kang   +6 more
wiley   +1 more source

Oxygen Partial Pressure as a Kinetic Descriptor for Single‐Crystal Morphology in Mid‐Nickel Layered Cathodes

open access: yesAdvanced Science, EarlyView.
Scalable synthesis of single‐crystal mid‐nickel cathodes demands precise kinetic control over competing densification and grain growth. Oxygen partial pressure emerges as a quantitative descriptor of effective grain‐boundary mobility, acting through changes in the apparent sintering activation barrier.
Hyeonho Park   +9 more
wiley   +1 more source

Climatic and Hydrological Changes Drive Contemporary Fire Regime Transitions in the World's Largest Wetland. [PDF]

open access: yesGlob Chang Biol
Barros-Rosa L   +17 more
europepmc   +1 more source

ELF5‐Mediated Enhancer–Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland

open access: yesAdvanced Science, EarlyView.
In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Xinmiao Wu   +11 more
wiley   +1 more source

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