Results 81 to 90 of about 586,453 (261)

Covered Interest-Rate Parity Revisited: an Extreme Value Copula Analysis

open access: yesAnuario Facultad de Ciencias Económicas y Empresariales, 2015
This article studied the covered interest-rate parity (CIP) condition under extreme market movements using extreme value theory and extreme value copulas to characterize dependence between extreme interest rate differentials and forward premium.
Mikel Ugando-Peñate
doaj  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

The Probability of the May 2024 Geomagnetic Superstorm

open access: yesSpace Weather
In May 2024, a series of coronal mass ejections resulted in the first “severe” (G4‐level) geomagnetic storm watch in nearly 20 years. This event evolved into a significant space weather event, including an “extreme” (G5) geomagnetic storm, moderate (S2 ...
S. Elvidge, D. R. Themens
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Investigating the Joint Probability of High Coastal Sea Level and High Precipitation

open access: yesJournal of Marine Science and Engineering
The design strategies for flood risk reduction in coastal towns must be informed by the likelihood of flooding resulting from both precipitation and coastal storm surge.
Namitha Viona Pais   +2 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli   +5 more
wiley   +1 more source

Influence of Major Hurricanes “Helene” and “Milton” in 2024 on EVA of the Long Ocean Water Level Record at Key West, USA

open access: yesCoasts
This paper investigates the influence of back-to-back major hurricanes “Helene” and “Milton” which devastated south-eastern regions of the USA in 2024, and the extent to which associated storm surges influenced Extreme Value Analysis (EVA) of the long ...
Phil J. Watson
doaj   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

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