Results 121 to 130 of about 9,847,764 (300)

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Extreme Value GARCH modelling with Bayesian Inference [PDF]

Extreme value theory is widely used financial applications such as risk analysis, forecasting and pricing models. One of the major difficulties in the applications to finance and economics is that the assumption of independence of time series ...
Les Oxley, Xin Zhao, Marco Reale, Carl Scarrott   +3 more
core  

Varying the VaR for Unconditional and Conditional Environments [PDF]

Accurate forecasting of risk is the key to successful risk management techniques. Using the largest stock index futures from twelve European bourses, this paper presents VaR measures based on their unconditional and conditional distributions for single ...
John Cotter
core   +2 more sources

Extremal Unicyclic Graphs for the Euler Sombor Index: Applications to Benzenoid Hydrocarbons and Drug Molecules

Axioms
With geometric significance, the Euler Sombor index of a graph Γ is defined as EP(Γ)=∑{uv}∈E(Γ)d(u)2+d(v)2+d(u)d(v). It originates from the mathematical distance property and has been proven to have good chemical applications in octane isomers.
Zhenhua Su, Zikai Tang
doaj   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Modelling extreme financial returns of global equity markets [PDF]

Extreme asset price movements appear to be more pronounced recently and have major consequences for an economy’s financial stability and monetary policies.
Cotter, John
core  

An Estimation of Risk Measures: Analysis of a Method

Computer Sciences & Mathematics Forum
Extreme value theory comprises a set of techniques for inference at the tail of distributions, where data are scarce or non-existent. The tail index is the main parameter, with risk measures such as value at risk or expected shortfall depending on it. In
Marta Ferreira, Liliana Monteiro
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

The size distribution of innovations revisited: an application of extreme value statistics to citation and value measures of patent significance [PDF]

This paper focuses on the analysis of size distributions of innovations, which are known to be highly skewed. We use patent citations as one indicator of innovation significance, constructing two large datasets from the European and US Patent Offices at ...
Verspagen,Bart, Silverberg,Gerald
core  

Spatio-temporal Distribution Characteristics and Future Trend Analysis of Extreme Climate Indices in Nenjiang River Basin over the Past 60 Years

Renmin Zhujiang
The study of extreme climate change in the Nenjiang River Basin is of great significance for ensuring ecological security and agricultural production.
GONG Xiao, DAI Changlei, LI Shuling, XIAO Yue   +3 more
doaj   +2 more sources