Results 61 to 70 of about 149,697 (269)

Extremal Properties of Extreme Value Distributions

open access: yesThe Annals of Mathematical Statistics, 1951
The upper and lower bounds for the expectation, the coefficient of variation, and the variance of the largest member of a sample from a symmetric population are discussed. The upper bound for the expectation (Table 1, Fig. 1), the lower bound for the C.V. (Table 2, Fig. 4) and the lower bound for the variance (Fig.
openaire   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Statistical‐Physical Adversarial Learning From Data and Models for Downscaling Rainfall Extremes

open access: yesJournal of Advances in Modeling Earth Systems
Quantifying the risk from extreme weather events in a changing climate is essential for developing effective adaptation and mitigation strategies. Climate models capturing different scenarios are often the starting point for physical risk.
Anamitra Saha, Sai Ravela
doaj   +1 more source

Extent and nature of climate change and its impact on public security risks

open access: yesJournal of Modern Science
Climate change is currently one of the most important challenges faced by mankind. The purpose of this article is to give a coherent account of the scope and nature of these changes and their impact on universal security threats.
Barbara Szykuła-Piec   +1 more
doaj   +1 more source

GEOMETRIC IDENTITIES IN STEREOLOGICAL PARTICLE ANALYSIS

open access: yesImage Analysis and Stereology, 2011
The paper reviews recent findings about geometric identities in integral geometry and geometric tomography, and their statistical application to stereological particle analysis. Open questions are discussed.
Stephan Kötzer
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Agro-technology for climate-smart agriculture and resilience to climate extremes in sub-Saharan Africa

open access: yesEnvironmental Research: Food Systems
Agro-technologies such as irrigation and new crop varieties can reduce climate risk for agricultural production in sub-Sahara Africa (SSA). SSA has the highest maize yield gaps globally, despite its importance as a staple crop in the region.
Laura Arenas-Calle   +2 more
doaj   +1 more source

The Extremal Quotient

open access: yesThe Annals of Mathematical Statistics, 1950
The extremal quotient is defined as the ratio of the largest to the absolute value of the smallest observation. Its analytical properties for symmetrical, continuous and unlimited distributions are obtained from a study of the auto-quotient defined as the ratio of two non-negative variates with identical distributions.
Gumbel, E. J., Keeney, R. D.
openaire   +3 more sources

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

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