Results 61 to 70 of about 504 (141)

A stable GH31 α-glucosidase as a model system for the study of mutations leading to human glycogen storage disease type II

Journal of Enzyme Inhibition and Medicinal Chemistry
GH31 glycosidases are widespread across organisms, but remarkably, less than 1% of them have been biochemically characterised to date. Among them, human lysosomal acid α-glucosidase (GAA) stands out due to its link to Pompe disease, a rare lysosomal ...
Roberta Iacono, Francesca Maria Pia Paragliola, Andrea Strazzulli, Marco Moracci   +3 more
doaj   +1 more source

Structural Characterization of the Xi Class Glutathione Transferase From the Haloalkaliphilic Archaeon Natrialba magadii

Frontiers in Microbiology, 2019
Xi class glutathione transferases (GSTs) are a recently identified group, within this large superfamily of enzymes, specifically endowed with glutathione-dependent reductase activity on glutathionyl-hydroquinone.
Adele Di Matteo, Luca Federici, Luca Federici, Michele Masulli, Erminia Carletti, Erminia Carletti, Daniele Santorelli, Daniele Santorelli, Jennifer Cassidy, Francesca Paradisi, Francesca Paradisi, Carmine Di Ilio, Nerino Allocati   +12 more
doaj   +1 more source

Biotechnological applications of archaeal enzymes from extreme environments

Biological Research, 2018
To date, many industrial processes are performed using chemical compounds, which are harmful to nature. An alternative to overcome this problem is biocatalysis, which uses whole cells or enzymes to carry out chemical reactions in an environmentally ...
Ma. Ángeles Cabrera, Jenny M. Blamey
doaj   +1 more source

Isolation and Characterization of a Thermaerobacillus caldiproteolyticus-like Strain Producing Extracellular Amylase from the Nelumwewa Geothermal Spring, Sri Lanka

Fermentation
The growing demand for efficient sustainable biocatalysts for industrial applications has driven the exploration of extremozymes from extremophiles, particularly those thriving in geothermal environments.
Sarath Bandara, Buddhika Dharmasena, Lakshani Pathirana, Prasad Jayasooriya, Aruna Weerasooriya   +4 more
doaj   +1 more source

Cloning, overexpression, purification, and characterization of a polyextremophilic β-galactosidase from the Antarctic haloarchaeon Halorubrum lacusprofundi

BMC Biotechnology, 2013
Background Halorubrum lacusprofundi is a cold-adapted halophilic archaeon isolated from Deep Lake, a perennially cold and hypersaline lake in Antarctica.
Karan Ram, Capes Melinda D, DasSarma Priya, DasSarma Shiladitya   +3 more
doaj   +1 more source

Marine Extremophiles: A Source of Hydrolases for Biotechnological Applications

Marine Drugs, 2015
The marine environment covers almost three quarters of the planet and is where evolution took its first steps. Extremophile microorganisms are found in several extreme marine environments, such as hydrothermal vents, hot springs, salty lakes and deep-sea
Gabriel Zamith Leal Dalmaso, Davis Ferreira, Alane Beatriz Vermelho   +2 more
doaj   +1 more source

Editorial: Advances in biotechnological applications of extreme microorganisms

Frontiers in Microbiology, 2023
Kattia Núñez-Montero, Leticia Barrientos, Zeinab G. Khalil, Angelina Lo Giudice   +3 more
doaj   +1 more source

A Pipeline for the Isolation and Cultivation of Microalgae and Cyanobacteria from Hypersaline Environments

Microorganisms
Microorganisms in high-salinity environments play a critical role in biogeochemical cycles, primary production, and the biotechnological exploitation of extremozymes and bioactive compounds.
Petra Tavčar Verdev, Marko Dolinar
doaj   +1 more source

Editorial: Enzyme design methodologies to enhance enzymatic yield. [PDF]

Front Bioeng Biotechnol, 2023
Runthala A, Tamil Selvan S, Kumaraguru T.   +2 more
europepmc   +1 more source

Prospective Roles of Extremophilic Fungi in Climate Change Mitigation Strategies

Journal of Fungi
Climate change and the resultant environmental deterioration signify one of the most challenging problems facing humankind in the 21st century. The origins of climate change are multifaceted and rooted in anthropogenic activities, resulting in increasing
Imran Ali, Hina Qaiser, Roheena Abdullah, Afshan Kaleem, Mehwish Iqtedar, Irfana Iqbal, Xiaoming Chen   +6 more
doaj   +1 more source