Results 31 to 40 of about 1,265,705 (294)
Icons are eye-cons: they provide a distillation of a complex object or idea into a simple pictorial shape. They create the impression of representing that which cannot be presented. Even at the level of the photograph, the links between icon and object are tenuous.
openaire +4 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The individual as moderator of variable relations – A configural approach
Moderators are variables that change the relations among other variables. Moderators are variables that are substantive just as the variables whose relations are moderated. In the present article, we propose using individuals as moderators. Specifically,
Alexander von Eye, Wolfgang Wiedermann
doaj +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Conjunctival leiomyosarcoma: A case report and review of literature
Leiomyosarcoma is a malignant mesenchymal tumor that is very uncommon in the conjunctiva. Nevertheless, we describe here the clinical manifestations, management, and prognosis of a rare case of leiomyosarcoma in this location.
Tania Lopez Montes +3 more
doaj +1 more source
Statistical Eye Model for Normal Eyes [PDF]
To create a binocular statistical eye model based on previously measured ocular biometric data.Thirty-nine parameters were determined for a group of 127 healthy subjects (37 male, 90 female; 96.8% Caucasian) with an average age of 39.9 ± 12.2 years and spherical equivalent refraction of -0.98 ± 1.77 D.
Rozema, Jos +2 more
openaire +4 more sources
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Ankylosing Spondylarthritis and Oculopathies
Oculopathies in ankilosing spondylarthritis are diagnosed in 29 % of examined patients in the ratio «uveit — scleritis — cataract — keratitis — glaucoma — conjunctivitis» as 7 : 5 : 2 : 2 : 2 : 1, thus, pathology of eyes determines the degree of activity
А.K. Pavlyuchenko +2 more
doaj +1 more source

