Results 51 to 60 of about 1,090,579 (275)

Optical Coherence Tomography in an Infant with Walker-Warburg Syndrome

Case Reports in Ophthalmology, 2015
Purpose: Walker-Warburg syndrome (WWS) is a type of congenital muscular dystrophy (CMD) characterised by severe brain malformation, lissencephaly, and congenital eye abnormalities.
Natsuko Mano, Tatsuma Mitsutsuji, Yamato Yoshikawa, Makiko Miyamoto, Hiroko Watanabe, Kazuhiro Shimizu, Michiko Miki, Masashi Mimura, Mari Ueki, Tsunehiko Ikeda   +9 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Insular volume abnormalities associated with different transition probabilities to psychosis [PDF]

, 2011
Background Although individuals vulnerable to psychosis show brain volumetric abnormalities, structural alterations underlying different probabilities for later transition are unknown.
McGuire, P., A. Riecher-Rössler, Simon, A., Simon, A, P. Fusar-Poli, Lenz, C., Fusar-Poli P., Riecher-Rössler, A., Bendfeldt, K, Stieglitz, R D, Riecher-Rössler, A, S. J. Borgwardt, McGuire, P, Borgwardt, S. J., J. Aston, Smieskova R., Bendfeldt K., Lenz C., Smieskova, R., Borgwardt, S J, Riecher-Rossler A., R. Smieskova, Riecher-Roessler, A., P. McGuire, Fusar-Poli, P, Simon A., A. Simon, Borgwardt S. J., K. Bendfeldt, Aston, J, Bendfeldt, K., Stieglitz, R. -D., Lenz, C, Stieglitz R. -D., Stieglitz, R.-D., R.-D. Stieglitz, Fusar-Poli, P., Aston J., McGuire P., Fusar-Poli, P.; id_orcid, Smieskova, R, C. Lenz, Aston, J.   +42 more
core   +2 more sources

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Eye Movement Abnormalities in Glaucoma Patients: A Review

Eye and Brain, 2022
Matthew A McDonald,1 Clark H Stevenson,1 Hannah M Kersten,2,3 Helen V Danesh-Meyer1,3 1Department of Ophthalmology, University of Auckland, Auckland, New Zealand; 2School of Optometry and Vision Science, University of Auckland, Auckland, New Zealand ...
McDonald MA, Stevenson CH, Kersten HM, Danesh-Meyer HV   +3 more
doaj  

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera, Agnese Tamanti, Silvia Messina, Nicola Dall'Osto, Teresa Maltempo, Stefano Ziccardi, Matteo Foschi, Maria Grazia Piscaglia, Diana Ferraro, Francesco Crescenzo, Francesca Rossi, Albulena Bajrami, Sabrina Marangoni, Damiano Marastoni, Francesca Benedetta Pizzini, Maria Isabel Leite, Roberta Magliozzi, Patrick Waters, Massimiliano Calabrese, Jacqueline Palace, Ruth Geraldes   +20 more
wiley   +1 more source

Molecular insights into the eye evolution of bivalvian molluscs [PDF]

, 2006
The intention of my PhD project was to gain more insights into eye evolution and to provide further evidence for the recently proposed idea that all eye-types found in eumetazoans derive from a common Pax6-dependent proto-type eye (Gehring and Ikeo, 1999)
Keller, Lukas Emanuel
core   +1 more source

Schizophrenia and Orthoptic Conditions: A Literature Review

British and Irish Orthoptic Journal
Purpose: A narrative review of the literature reporting ocular abnormalities in patients with schizophrenia was undertaken to determine the types and prevalence of orthoptic conditions in this patient cohort.
Anna McBride, Gemma Arblaster
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source