Results 51 to 60 of about 660,881 (302)
An adaptive perception-based image preprocessing method [PDF]
, 2015 The aim of this paper is to introduce an adaptive preprocessing procedure based on human perception in order to increase the performance of some standard image processing techniques.
BRUNI, VITTORIA +3 more
core +1 more source
ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology
Advanced Science, EarlyView.This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li +25 more
wiley +1 more source
Targeting Herpetic Keratitis by Gene Therapy
Journal of Ophthalmology, 2012 Ocular gene therapy is rapidly becoming a reality. By November 2012, approximately 28 clinical trials were approved to assess novel gene therapy agents.
Hossein Mostafa Elbadawy +4 more
doaj +1 more source
How do we acquire understanding of conceptual models? [PDF]
, 2015 In organizations, conceptual models are used for understanding the domain concepts. Such models are crucial in analysis and development of information systems.
Bera, Palash, Poels, Geert
core
Safety implications of a pedestrian protection system - the driver's point of view [PDF]
, 2007 Pedestrians can sustain fatal injuries, even in low-speed collisions. Active pedestrian protection systems, such as an Active Bonnet, have been shown to mitigate the outcome of a collision.
Hamson, A.H., Jamson, S.L.
core +1 more source
Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance
Advanced Science, EarlyView.DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin +15 more
wiley +1 more source
Major impact from a minor merger - The extraordinary hot molecular gas flow in the Eye of the NGC 4194 Medusa galaxy [PDF]
, 2018 Minor mergers are important processes contributing significantly to how galaxies evolve across the age of the Universe. Their impact on supermassive black hole growth and star formation is profound.
Aalto, S. +8 more
core +3 more sources
Advanced Science, EarlyView.Reprogramming tumor‐associated macrophages is a promising therapeutic strategy for solid tumors. Here, a nitric oxide (NO)‐activatable NIR‐II fluorescence/photoacoustic nanoinducer (I/E@M2pep) that simultaneously facilitates and visualizes the repolarization of TAMs to an M1‐like phenotype is reported, thereby enhancing anti‐tumor efficacy through M1 ...
Qian Chen +8 more
wiley +1 more source
Changing pattern of utilization of human donor cornea in India
Indian Journal of Ophthalmology, 2015 Purpose: To review the changing pattern of donor, corneal utilization in an eye bank at a Tertiary Care Center in Northern India by analyzing the trend in the years 2003, 2008, and 2011.
Varun Gogia +4 more
doaj +1 more source
Advanced Energy Materials, EarlyView.A multimodal strategy creates efficient semi‐transparent perovskite solar cells with a record 4.29% light utilization efficiency and 22.41% indoor performance. This approach enables the first scalable 30 x 30 cm2 semi‐transparent solar module, highlighting its potential for building‐integrated and indoor photovoltaics.
Siming Huang +16 more
wiley +1 more source