Results 181 to 190 of about 1,749,298 (295)
Loss of ANK3 Function Causes a Recessive Neurodevelopmental Disorder with Cerebellar Ataxia
Abstract Background ANK3 encodes ankyrin‐G, a key scaffolding protein essential for neuronal function. While both monoallelic and biallelic ANK3 variants have been linked to neurodevelopmental disorders (NDDs), existing evidence for their pathogenicity and clinical correlation remains limited and heterogeneous.
Reza Maroofian+11 more
wiley +1 more source
Abstract Background Visual hallucinations (VHs) are a common feature of Parkinson's disease (PD) believed to arise from disruptions to the functional architecture supporting sensory integration and attentional control. Across synucleinopathies, increased pathological burden in the amygdala and deficits in cholinergic modulation have been linked to VHs.
Anna Ignatavicius+6 more
wiley +1 more source
Back to the Mission. Revisiting Slack in Nonprofits and Introducing Tappable Slack
ABSTRACT This article contributes to and develops the previous literature on excess resources (“slack”) in nonprofit organizations through a conceptual analysis of the implications that the organizational distinctiveness of nonprofits carries for our understanding of slack in these organizations.
Marta Reuter+2 more
wiley +1 more source
The study investigates the sedative potential of naringenin (NAR) through in vivo and in silico approaches. NAR significantly enhances sleep duration and reduces latency in mice, especially when combined with diazepam. Molecular docking shows strong binding to GABAA receptors, suggesting a GABAergic mechanism.
Dipu Bishwas+8 more
wiley +1 more source
This paper presents a comprehensive overview of recent advancements in Joule‐heating synthesis of photo and electrocatalysts, emphasizing its benefits and applications. The objective is to offer an effective strategy for enhancing the diversity and performance of catalytic materials.
Jiaqi Li+4 more
wiley +1 more source
Iguratimod alleviated Sjögren's syndrome through regulating macrophage polarization
Nonobese diabetic (NOD) mice exhibited characteristic of Sjögren's syndrome (SS), with increased M1 macrophages and deceased M2 macrophages. Iguratimod alleviated SS‐like symptoms and restored balance of macrophage polarization through inhibiting the mitogen‐activated protein kinases pathway in NOD mice.
Junqiao Guo+7 more
wiley +1 more source
Psychometric Evaluation and Computerized Adaptive Testing Simulations of Myopic Refractive Intervention Quality of Life Item Banks. [PDF]
Man REK+9 more
europepmc +1 more source