Results 81 to 90 of about 6,915,529 (403)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A comparative evaluation of deep learning approaches for ophthalmology

Scientific Reports
There is a growing number of publicly available ophthalmic imaging datasets and open-source code for Machine Learning algorithms. This allows ophthalmic researchers and practitioners to independently perform various deep-learning tasks.
Glenn Linde, Waldir Rodrigues de Souza Jr, Renoh Chalakkal, Helen V. Danesh-Meyer, Ben O’Keeffe, Sheng Chiong Hong   +5 more
doaj   +1 more source

Prevalence of Eye Problems among Young Infants of Rohingya Refugee Camps: Findings from a Cross-Sectional Survey

Tropical Medicine and Infectious Disease, 2020
Early detection of pediatric eye problems can prevent future vision loss. This study was to estimate the prevalence of common eye problems among infants born in a resource-constrained emergency setting with a broader aim to prevent future vision loss or ...
AHM Enayet Hussain, Zunayed Al Azdi, Khaleda Islam, ANM Ehtesham Kabir, Rumana Huque   +4 more
doaj   +1 more source

IMI – industry guidelines and ethical considerations for myopia control report [PDF]

, 2019
PURPOSE. To discuss guidelines and ethical considerations associated with the development and prescription of treatments intended for myopia control (MC). METHODS.
Drove, Bjorn, Gifford, Kate L, Gonzalez-meijome, Jose Manuel, Gray, Lyle, Jones, Lyndon, Kratzer, Timo, Newman, Steve, Nichols, Jason J, Ohlendorf, Arne, Ramdass, Stephanie, Resnikoff, Serge, Santadomigo-Rubido, Jacinto, Schmid, Katrina L, Tan, Donald, Tan, Kai-Ooh, Vera-Diaz, Fuensanta A, Wong, Yee-Ling   +16 more
core   +1 more source

Spectrum of eye disorders in diabetes (SPEED) in India: Eye care facility based study. Report # 1. Eye disorders in people with type 2 diabetes mellitus

Indian Journal of Ophthalmology, 2020
Purpose: To document the spectrum of eye diseases in people with type 2 diabetes mellitus (T2DM) reporting to large eye care facilities in India. Methods: The selection of eye care facilities was based on the zone of the country and robustness of the ...
T. Das, U. Behera, H. Bhattacharjee, C. Gilbert, G. Murthy, R. Rajalakshmi, Hira B. Pant, Rajan Shukla   +7 more
semanticscholar   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

An Unusual Case of Extensive Lattice Degeneration and Retinal Detachment [PDF]

Journal of Clinical and Diagnostic Research, 2016
Lattice degeneration of the retina is not infrequently encountered on a dilated retinal examination and many of them do not need any intervention. We report a case of atypical lattice degeneration variant with peripheral retinal detachment.
David J. Mathew, Saurabh Kumar Sarma, Jennifer V. Basaiawmoit   +2 more
doaj   +1 more source

Implementing the Affordable Care Act: Key Design Decisions for State-Based Exchanges [PDF]

, 2013
The Affordable Care Act requires the establishment of new health insurance marketplaces -- known as exchanges -- in every state by October 1, 2013. This report examines key design decisions made by the 17 states and the District of Columbia that chose to

core  

Eye drop Self-medication: Comparative Questionnaire-based study of two Latin American cities. [PDF]

, 2014
A broad spectrum of ocular symptoms are treated by self-medication with commercial eye-drops.  This behavior threatens individuals' visual health. In Latin America, evidence is poor.
Gramajo, Ana L., Hildegard Piñeros-Heilbron, Juarez, Claudio P., Luna, José D., Marquez, Gabriel, Peña, Fernando, Sanchez, Victoria M., Torres, Victor Eduardo Roque   +7 more
core   +1 more source

COVID-19: Limiting the Risks for Eye Care Professionals

Ocular immunology and inflammation, 2020
After the outbreak of the disease COVID-19, it has reached pandemic proportions within a very short time. It is mainly transmitted human-to-human through direct contact with secretions from an infected person or through inhalation of droplets containing ...
Soumen Sadhu, Rupesh V Agrawal, Richa Pyare, C. Pavesio, M. Zierhut, Anadi Khatri, Justine R. Smith, M. D. de Smet, J. Biswas   +8 more
semanticscholar   +1 more source