Results 141 to 150 of about 865,702 (329)

Assessment of human resource for eye health services in Southern Ethiopia

open access: yesHuman Resources for Health
Background Human resources related to eye health are critical to significant reductions in blindness and low vision on a global and regional scale. Blindness and visual impairment affect the quality of life, poverty rates, and employment and educational ...
Zelalem Mehari, Ashiyana Nariani
doaj   +1 more source

Generating evidence for planning eye care service delivery in an urban underprivileged population setting in Pune, Western India [PDF]

open access: gold, 2019
Sucheta Kulkarni   +9 more
openalex   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

open access: yesAdvanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao   +19 more
wiley   +1 more source

Strategies for pricing publicly provided health services [PDF]

open access: yes
The authors examine how governments finance and allocate public spending, with an eye to developing strategies for pricing publicly provided health services.
Gertler, Paul J., Hammer, Jeffrey S.
core  

Syntaxin 3B Mediates Light‐Dependent Interactions with STXBP1 and Arrestin 4: Distinct Roles in Rods and Cones

open access: yesAdvanced Science, EarlyView.
The present study investigates a cone‐specific STX3 knockout model, displaying a complete loss of cone function, a later onset reduction in rod function, and photoreceptor cell death. A cone‐specific depletion of STXBP1 and ARR4 could be observed in this model.
Lars Tebbe   +5 more
wiley   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

open access: yesAdvanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang   +8 more
wiley   +1 more source

Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning

open access: yesAdvanced Science, EarlyView.
Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao   +14 more
wiley   +1 more source

Evaluating the access and utilization of eyecare services after the adoption of eyecare PBF and its financial sustainability: the case of Rwanda

open access: yesBMC Health Services Research
Introduction Sustainable improvements in eye care outcomes has been a concern for policy makers in low- and middle-income countries (LMICs). We examined the changes in access and utilization of eye care service at primary care level and explored ...
James Humuza   +13 more
doaj   +1 more source

OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain

open access: yesAdvanced Science, EarlyView.
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang   +10 more
wiley   +1 more source

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