Results 171 to 180 of about 563,019 (246)

The role of mycophenolate mofetil in the therapy of thyroid eye disease. [PDF]

Ther Adv Endocrinol Metab
Witowska A, Pawluczuk E, Szczepanek-Parulska E, Ruchala M.   +3 more
europepmc   +1 more source

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

Advanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu, Xuedi Zhang, Ying Zhou, Jie Zheng, Angyang Sun, Kailong Zhuang, Weiwei Bao, Guanjun Gao   +7 more
wiley   +1 more source

Clinical profiles of thyroid eye disease with and without strabismus: a comparative study. [PDF]

Int J Ophthalmol
Khorrami-Nejad M, Akbari MR, Azizi E, Saad SD, Majdi A, Daneshvar K, Rafizadeh SM.   +6 more
europepmc   +1 more source

Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound

Advanced Science, EarlyView.
In this study, Qiu et al. found that low‐intensity ultrasound can directly activate sparse ultrasound‐sensitive neurons (UNs) in the primary visual cortex (V1) of deafened mice. The proportion of these sparse UNs is pressure‐dependent. Furthermore, ultrasound modulates visual circuitry with distinct excitatory and inhibitory effects.
Jiaru He, Jiejun Zhu, Xinxin Wang, Zihao Chen, Jin Yang, Zhen Yuan, Hongzhi Xu, Lei Sun, Zhihai Qiu   +8 more
wiley   +1 more source

A comprehensive analysis of dry eye disease clinical trials (2000-2024): research trends and gaps. [PDF]

Front Pharmacol
Jiang X, Xu B, Xu R, Wu N, Tian S, Peng H, Zhao YE.   +6 more
europepmc   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

Beyond the Genome: Can Epigenetics Forecast Therapeutic Success in Graves' Disease and Thyroid Eye Disease? [PDF]

Int J Mol Sci
Manso J, Sardone D, Marotta V, Salcuni AS, Brunetti A, Cipri C, Sciannimanico SM, Piva L, Carpentieri M, Falchetti A, Vescini F.   +10 more
europepmc   +1 more source

A Wireless, Battery‐Free Artificial Throat Patch with Deep Learning for Emotional Speech Recognition

Advanced Science, EarlyView.
In this work, Xu and co‐workers develop a wireless, battery‐free artificial throat patch system (ATPS) consisting of a carbon nanotube‐based thin‐film strain sensor and a miniaturized flexible printed circuit board, to enable real‐time sensing of throat signals.
Bingxin Xu, Guanming Lin, Xiaohui Hong, Chuting Liu, Xinyi Qu, Kangjian Jiao, Lei Zhang, Bingzhe Xu, Jun Yan, Yancong Qiao, Xudong Lin   +10 more
wiley   +1 more source

Redefining evidence for teprotumumab in thyroid eye disease: an updated meta-analysis of efficacy and safety. [PDF]

Front Endocrinol (Lausanne)
Song R, Zhao W, Li S, Niu X, Guo J, Zhang X, Zhang X, Ji L.   +7 more
europepmc   +1 more source