Results 241 to 250 of about 10,104,948 (391)

Varenicline Solution Nasal Spray for the Treatment of Dry Eye Disease in Sjogren's Disease: A Pilot Study. [PDF]

open access: yesClin Ophthalmol
Gupta AS   +7 more
europepmc   +1 more source

Activation of Glutamatergic Neurons in the Supramammillary Nucleus Promotes the Recovery of Consciousness under Sevoflurane Anesthesia

open access: yesAdvanced Science, EarlyView.
Selective lesioning of SuM glutamatergic neurons promoted the induction of and delayed emergence from sevoflurane anesthesia and increased sevoflurane sensitivity. Optogenetic stimulation of SuM glutamatergic neurons or the SuM‐MS projection promoted behavioral arousal and cortical activation under steady‐state sevoflurane anesthesia and reduced the ...
Jiayan Li   +8 more
wiley   +1 more source

Secret in the eyes - fish eye disease

open access: yesIndian Journal of Nephrology, 2016
P Rajesh, PK Maharana, Vaibhav Ingle
openaire   +3 more sources

Identification of glutamine as a potential therapeutic target in dry eye disease. [PDF]

open access: yesSignal Transduct Target Ther
Chen X   +14 more
europepmc   +1 more source

Interpretable Multimodal Fusion Model for Bridged Histology and Genomics Survival Prediction in Pan‐Cancer

open access: yesAdvanced Science, EarlyView.
This article introduces the Brim model, an interpretable multimodal fusion framework that integrates histopathology, genomics, and transcriptomics to enhance cancer prognosis prediction. Addressing real‐world data limitations, the model enables precise predictions even with incomplete molecular data.
Feng Gao   +9 more
wiley   +1 more source

Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa   +6 more
wiley   +1 more source

Epithelial Cell Mechanoresponse to Matrix Viscoelasticity and Confinement Within Micropatterned Viscoelastic Hydrogels

open access: yesAdvanced Science, EarlyView.
Extracellular matrix (ECM) viscoelasticity and spatial confinement regulate cellular processes such as cancer progression, yet their interplay remains poorly understood. By developing fibronectin (FN)‐micropatterned viscoelastic hydrogels mimicking breast cancer mechanics, this study explores breast epithelial cell mechanoresponse to ECM ...
Giuseppe Ciccone   +6 more
wiley   +1 more source

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