Results 81 to 90 of about 10,425,533 (356)

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

open access: yesFEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki   +11 more
wiley   +1 more source

Patient Reported Differences in Dry Eye Disease between Men and Women: Impact, Management, and Patient Satisfaction [PDF]

open access: yes, 2014
Purpose Dry eye disease affects women twice as often as men, but there is little information on whether dry eye treatments, treatment satisfaction, or the impact of dry eye disease on patients’ lives and vision might differ by sex.
Buring, Julie E.   +5 more
core   +2 more sources

The edge visualization metric: Quantifying the improvement of lung SBRT target definition with 4D CBCT

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Four‐dimensional cone‐beam CT (4D CBCT) incorporates oversampling of 3D data to reconstruct multi‐phase CBCT data sets representing distinct phases of the breathing cycle based on a diaphragmatic correlate of respiratory motion. Motion artifacts and blurring can be reduced relative to three‐dimensional cone‐beam (3D CBCT), allowing ...
Colton Baley   +4 more
wiley   +1 more source

Orbitofrontal cholesterol granuloma masquerading as frontal sinus mucoceles: report of two cases

open access: yesBMC Ophthalmology, 2023
Background Two cases of orbitofrontal cholesterol granuloma masquerading as frontal sinus mucoceles were reported to understand image findings, clinical and histopathologic features of orbitofrontal cholesterol granuloma to improve its diagnosis and ...
Ruimiao Li   +5 more
doaj   +1 more source

P38 Mitogen-Activated Protein Kinase Protects Against Retinoblastoma Through Regulating USP22/SIRT1/SOST Axis

open access: yesFrontiers in Oncology, 2022
Retinoblastoma (RB) is the most common intraocular malignancy in children. It has been previously reported that p38 MAPK is related to the pathogenesis of RB. Here we aim at investigating how p38 MAPK affected RB progression through mediating USP22/SIRT1/
Xiaoming Huang   +10 more
doaj   +1 more source

Incidence of symptomatic toxoplasma eye disease: aetiology and public health implications. [PDF]

open access: yes, 1999
Ocular disease is the commonest disabling consequence of toxoplasma infection. Incidence and lifetime risk of ocular symptoms were determined by ascertaining affected patients in a population-based, active reporting study involving ophthalmologists ...
Dunn, DT   +8 more
core   +2 more sources

Radiotherapy medical physics in the Philippines: A contemporary overview

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose With cancer ranking as the third leading cause of death in the Philippines and a disparity in healthcare resources across regions, this research aimed to assess the state of radiotherapy medical physics in the country. Methodology The study utilized a comprehensive online survey with 94 structured questions answered by 19 clinics ...
John Paul C. Cabahug   +4 more
wiley   +1 more source

A Generic Pixel Pitch Calibration Method for Fundus Camera via Automated ROI Extraction

open access: yesSensors, 2022
Pixel pitch calibration is an essential step to make the fundus structures in the fundus image quantitatively measurable, which is important for the diagnosis and treatment of many diseases, e.g., diabetes, arteriosclerosis, hereditary optic atrophy, etc.
Tengfei Long   +9 more
doaj   +1 more source

Implementasi Metode Dempster Shafer dan Desain Basis Data pada Sistem Pakar Diagnosa Penyakit Mata [PDF]

open access: yes, 2017
Limited knowledge of the patient against eye disease becomes a problem and make the patient difficult to predict the eye disease he suffered. In this case, the patient will need an expert who can early diagnose eye disease in order to prevent early.
Diana, D. (Diana)
core   +2 more sources

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao   +34 more
wiley   +1 more source

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