Results 131 to 140 of about 6,948,099 (297)

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Assessing the prevalence of eye disease in the community [PDF]

Eye, 1995
openaire   +2 more sources

Symptomatic dry eye disease and associated factors among postgraduate students at Hawassa University, Sidama Region, Ethiopia

Scientific Reports
Dry eye disease and its symptoms are becoming an increasingly significant public health issue. This study aims to understand the extent of the disease, particularly in light of the post-COVID digital revolution.
Mikias Mered Tilahun, Henok Biruk Alemayehu, Biruk Lelisa Eticha, Getasew Alemu Mersha, Melkamu Temeselew Tegegn, Tarekegn Cheklie Zeleke, Nardos Hussen Abdulkadir, Abdisa Gemedi Jara, Ermias Solomon Yalew, Kalkidan Berhane Tsegaye, Merkineh Markos Lorato   +10 more
doaj   +1 more source

Epidemiology of Dry Eye in Patients With Autoimmune Disease

This cohort study investigates the prevalence, onset, and ocular surface damage of dry eye disease across major autoimmune diseases to clarify disease-specific characteristics among patients in ...
Sun, Chi-Chin, Chen, Nan-Ni, Huang, Yu-Tung   +2 more
core   +1 more source

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

Advanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li, Xi Wan, Xinru Su, Zechuan Li, Yue Wang, Ying Wang, Ruofei Li, Huangzhao Wei, Jianbin Zhang, Shuai Wang   +9 more
wiley   +1 more source

Prevalence and risk factors of dry eye symptoms in Jazan Province, Saudi Arabia: a cross-sectional study

Frontiers in Ophthalmology
PurposeDry eye syndrome (DES) is characterized by tear film and ocular surface disruptions. Symptomatic DES, one of the most common ocular diseases, reduces the quality of life. This study aimed to evaluate the prevalence of and possible risk factors for
Hatim Hassan Najmi, Abdulrahman Mohsen Tubayqi, Sultan Mousa Bakri, Abdullah Meshal Alsharif   +3 more
doaj   +1 more source

Prevalence of Childhood Eye Diseases

Turkiye Klinikleri Journal of Pediatrics, 2018
Özgün Melike GEDAR TOTUK, Kerem KABADAYI, Naz EKİZOĞLU, Tülay ARICI   +3 more
openaire   +1 more source

Temperature, Humidity and Regional Prevalence of Dry Eye Disease in Argentina

Medicina
Background and Objectives: To evaluate whether regional climatic factors, particularly relative humidity (RH) and temperature, are associated with geographic variation in dry eye disease (DED) prevalence in Argentina. Materials and Methods: A secondary analysis of a nationwide voluntary online cross-sectional survey of DED in Argentina (April 2022; non-
María C. Marini, Belén Liviero, Rodrigo M. Torres, Jeremías G. Galletti, Gustavo Galperin, Monica Alves, Jesús Merayo-Lloves   +6 more
openaire   +2 more sources

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source