Results 111 to 120 of about 951,865 (332)

Histidine nutrition and genotype affect cataract development in Atlantic salmon, Salmo salar L. [PDF]

, 2005
The aim of this study was to investigate effects of dietary levels of histidine (His) and iron (Fe) on cataract development in two strains of Atlantic salmon monitored through parr-smolt transformation.
Bjerkas, E, Breck, O, Campbell, P, Rhodes, J D, Sanderson, J, Waagbo, R   +5 more
core   +1 more source

Functional Connectivity Associations With Markers of Disease Progression in GRN Pathogenic Variant Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan, Stephanie A. Chu, Suvi Häkkinen, Liwen Zhang, David McFall, Jonathan D. Rohrer, Jesse A. Brown, Alex J. Lee, Kristen Fernhoff, Lorenzo Pasquini, Katherine P. Rankin, Maria Luisa Mandelli, Maria Luisa Gorno‐Tempini, Jennifer S. Yokoyama, Virginia E. Sturm, Brian Appleby, Bradford C. Dickerson, Kimiko Domoto‐Reilly, Tatiana Foroud, Daniel H. Geschwind, Nupur Ghoshal, Neill R. Graff‐Radford, Ging‐Yuek Robin Hsiung, Eric J. Huang, Edward Huey, Kejal Kantarci, Irene Litvan, Ian R. Mackenzie, Mario F. Mendez, Chiadi U. Onyike, Leonard Petrucelli, Eliana Marisa Ramos, Erik D. Roberson, Julio C. Rojas, Maria Carmela Tartaglia, Arthur W. Toga, Sandra Weintraub, Leah K. Forsberg, Hilary W. Heuer, Brad F. Boeve, Adam L. Boxer, Howard J. Rosen, Bruce L. Miller, Fermin Moreno, William W. Seeley, Suzee E. Lee, on behalf of the ALLFTD Consortium   +46 more
wiley   +1 more source

Plasma Glial Fibrillary Acidic Protein Correlates With Brain Metal Burden in Wilson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuroinflammation driven by extracellular copper contributes to neuronal damage in Wilson's disease (WD). This study investigated the relationship between brain metal burden and peripheral neuroinflammation markers in WD. Methods We conducted a cross‐sectional study involving 89 participants, including patients with WD (n = 63 ...
Sung‐Pin Fan, Ya‐Fang Chen, Cheng‐Hsuan Li, Yih‐Chih Kuo, Ni‐Chung Lee, Yin‐Hsiu Chien, Wuh‐Liang Hwu, Tai‐Chung Tseng, Tung‐Hung Su, Chien‐Ting Hsu, Huey‐Ling Chen, Chin‐Hsien Lin, Yen‐Hsuan Ni   +12 more
wiley   +1 more source

THE ROLE OF BRACHYTHERAPY IN THE TREATMENT OF RETINAL CAPILLARY HEMANGIOMAS

Российский офтальмологический журнал, 2018
Purpose: to evaluate the efficiency of brachytherapy treatment in capillary retinal hemangioma and the emerging complications. Material and methods. Between 2005 and 2014, 18 patients with capillary hemangioma of the retina (11 females and 7 males, mean ...
V. V. Neroev, S. V. Saakyan, P. A. Ilyukhin, V. V. Valskiy, M. V. Ryabina, A. Yu. Novikova   +5 more
doaj   +1 more source

The eye of Drosophila as a model system for studying intracellular signaling in ontogenesis and pathogenesis [PDF]

, 2018
Many human diseases are caused by malfunction of basic types of cellular activity such as proliferation, differentiation, apoptosis, cell polarization, and migration.
Katanaev, V., Kryuchkov, M.
core  

Reflections on the Utility of the Retina as a Biomarker for Alzheimer's Disease: A Literature Review. [PDF]

, 2019
As a part of the central nervous system, the retina may reflect both physiologic processes and abnormalities related to diseases of the brain. Indeed, a concerted effort has been put forth to understand how Alzheimer's disease (AD) pathology may manifest
Honma, Patrick, Ngolab, Jennifer, Rissman, Robert A   +2 more
core   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source

Frequency of Seroconversion in Aquaporin‐4 Antibody Testing: Insights From Real‐World Data

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Clinicians often repeat aquaporin‐4‐immunoglobulin G (AQP4‐IgG) testing in case of possible seroconversion. Compared with older, less sensitive immunofluorescence assays (IFA), cell‐based assays (CBA) offer higher sensitivity. This study assessed the frequency of seroconversion in a retrospective Cleveland Clinic cohort (2006–2024) of 451 ...
Tatchaporn Ongphichetmetha, Mengke Du, Nisa Vorasoot, Sean J. Pittock, Jeffrey A. Cohen, Amy Kunchok   +5 more
wiley   +1 more source

Ablation Depth-Dependent Survival Analysis of Phototherapeutic Keratectomy for Recurrent Corneal Erosion Syndrome

Ophthalmology and Therapy
Introduction Phototherapeutic keratectomy (PTK) is a treatment for recurrent corneal erosion syndrome (RCES). The aim of this study was to investigate whether deeper ablations yielded greater success rates.
Kunal A. Gadhvi, Georgios Vakros, Alfredo Borgia, Kirithika Muthusamy, Laura de Benito-Llopis, Alexander C. Day, Daniel M. Gore   +6 more
doaj   +1 more source

Evaluation of Flowmetry Indicators in Patients with a Wet AMD Form during Antiangiogenic Therapy

Oftalʹmologiâ, 2019
Purpose: to assess the effect of aflibercept (Eylea; “Regeneron”, USA) intravitreal injections on ocular blood flow and intraocular pressure parameters in patients with neovascular form of age-related macular degeneration (wet AMD).
N. Yu. Yousef, E. E. Kazaryan, D. M. Safonova, N. Yu. Shkolyarenko, F. B. Dudieva, T. V. Sharnina   +5 more
doaj   +1 more source