Results 111 to 120 of about 10,588,664 (388)
Is Household Air Pollution a Risk Factor for Eye Disease? [PDF]
, 2013 In developing countries, household air pollution (HAP) resulting from the inefficient burning of coal and biomass (wood, charcoal, animal dung and crop residues) for cooking and heating has been linked to a number of negative health outcomes, mostly ...Adair-Rohani, Heather, Araj, Houmam, Bates, Michael N., Chen, Dong Feng, Lee, David J., Lee, Jennifer S., Schaumberg, Debra A., West, Sheila K. +7 morecore +3 more sourcesGenetic Diversity and Expanded Phenotypes in Dystonia: Insights From Large‐Scale Exome Sequencing
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Dystonia is one of the most prevalent movement disorders, characterized by significant clinical and etiological heterogeneity. Despite considerable heritability (~25%), the etiology in most patients remains elusive. Moreover, understanding correlations between clinical manifestations and genetic variants has become increasingly ...Mirja Thomsen, Fabian Ott, Sebastian Loens, Gamze Kilic‐Berkmen, Ai Huey Tan, Shen‐Yang Lim, Ebba Lohmann, Kaja M. Schröder, Lea Ipsen, Lena A. Nothacker, Linn Welzel, Alexandra S. Rudnik, Frauke Hinrichs, Thorsten Odorfer, Kirsten E. Zeuner, Friederike Schumann, Andrea A. Kühn, Simone Zittel, Marius Moeller, Robert Pfister, Christoph Kamm, Anthony E. Lang, Yi Wen Tay, Ana Luísa de Almeida Marcelino, Marie Vidailhet, Emmanuel Roze, Joel S. Perlmutter, Jeanne S. Feuerstein, Victor S. C. Fung, Florence Chang, Richard L. Barbano, Steven Bellows, Aparna A. Wagle Shukla, Alberto J. Espay, Mark S. LeDoux, Brian D. Berman, Stephen Reich, Andres Deik, Andre Franke, Michael Wittig, Sören Franzenburg, Jens Volkmann, Norbert Brüggemann, H. A. Jinnah, Tobias Bäumer, Christine Klein, Hauke Busch, Katja Lohmann +47 morewiley +1 more sourceIL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis [PDF]
, 2015 Macrophage dysfunction plays a pivotal role during neovascular proliferation in diseases of ageing including cancers, atherosclerosis and blinding eye disease.Apte, Rajendra S, Gdoura, Abdelaziz, Kubota, Shunsuke, Nakamura, Rei, Santeford, Andrea, Sene, Abdoulaye, Zapata, Nicole +6 morecore +2 more sourcesRelevance of Kappa and Lambda Free Light Chains in Autoimmune Astrocytopathy Associated With Anti‐GFAP Antibodies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction
The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.Michael Levraut, Romain Marignier, Mikael Cohen, Jeanne Benoit, Cassandre Landes‐Chateau, Elisabeth Maillart, Marion Cremoni, Barbara Seitz‐Polski, Anne‐Laurie Pinto, Pauline Dumez, Jérôme Honnorat, Christine Lebrun‐Frenay +11 morewiley +1 more sourceCross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases
Nature Communications, 2018 Central corneal thickness (CCT) is a highly heritable trait associated with complex eye diseases such as keratoconus and glaucoma. We perform a genome-wide association meta-analysis of CCT and identify 19 novel regions.Adriana I. Iglesias, A. Mishra, V. Vitart, Y. Bykhovskaya, René Höhn, H. Springelkamp, G. Cuéllar-Partida, P. Gharahkhani, J. C. Bailey, C. Willoughby, Xiaohui Li, S. Yazar, A. Nag, A. Khawaja, O. Polašek, D. Siscovick, P. Mitchell, Y. Tham, J. Haines, L. Kearns, C. Hayward, Yuan Shi, E. V. van Leeuwen, K. Taylor, Jie Jin Elena John Rodney Elizabeth G. Tien Yin Paul N Wang Rochtchina Attia Scott Holliday Wong Baird Xi, J. Wang, E. Rochtchina, J. Attia, Rodney J. Scott, E. Holliday, Tien Y. Wong, P. Baird, Jing Xie, M. Inouye, A. Viswanathan, X. Sim, Pieter W. M. Bonnemaijer, J. Rotter, Nicholas G. Martin, T. Zeller, R. Mills, Emmanuelle Souzeau, Sandra E. Staffieri, J. Jonas, I. Schmidtmann, Thibaud S. Boutin, J. Kang, S. Lucas, Tien Y. Wong, M. Beutel, James F. Wilson, R. Rand Murray H. Donald L. William G. John David S. Allingham Brilliant Budenz Christen Fingert Friedm, R. Allingham, M. Brilliant, D. Budenz, W. Christen, J. Fingert, D. Friedman, D. Gaasterland, T. Gaasterland, M. Hauser, Peter Kraft, Richard K. Lee, P. Lichter, Yutao Liu, S. Loomis, S. Moroi, M. Pericak-Vance, A. Realini, J. Richards, J. Schuman, W. Scott, Kuldev Singh, A. Sit, D. Vollrath, R. Weinreb, G. Wollstein, D. Zack, Kang Zhang, Peter Ines Jenefer M. Elvira Matthew A. Juan P. Aiden Pa Donnelly Barroso Blackwell Bramon Brown Casas Corv, P. Donnelly, I. Barroso, J. Blackwell, E. Bramon, Matthew A. Brown, J. P. Casas, A. Corvin, P. Deloukas, A. Duncanson, Janusz Jankowski, Hugh S. Markus, C. Mathew, C. Palmer, R. Plomin, A. Rautanen, S. Sawcer, R. Trembath, N. Wood, C. Spencer, G. Band, C. Bellenguez, C. Freeman, G. Hellenthal, E. Giannoulatou, M. Pirinen, R. Pearson, A. Strange, Z. Su, Damjan Vukcevic, C. Langford, S. Hunt, S. Edkins, R. Gwilliam, H. Blackburn, S. Bumpstead, S. Dronov, M. Gillman, Emma V. Gray, Naomi Hammond, Alagurevathi Jayakumar, O. T. McCann, J. Liddle, Simon C. Potter, Radhi Ravindrarajah, M. Ricketts, M. Waller, P. Weston, S. Widaa, P. Whittaker, A. Uitterlinden, E. Vithana, P. Foster, P. Hysi, A. Hewitt, C. Khor, L. Pasquale, G. Montgomery, C. Klaver, T. Aung, N. Pfeiffer, D. Mackey, C. Hammond, Ching-Yu Cheng, J. Craig, Y. Rabinowitz, J. Wiggs, K. Burdon, C. V. van Duijn, S. Macgregor +148 moresemanticscholar +1 more sourceThe Cone Dysfunction Syndromes [PDF]
, 2016 The cone dysfunction syndromes are a heterogeneous group of inherited, predominantly stationary retinal disorders characterised by reduced central vision, and varying degrees of colour vision abnormalities, nystagmus and photophobia.Aboshiha, J, Carroll, J, Dubis, AM, Harcastle, AJ, Michaelides, M +4 morecore