Results 171 to 180 of about 23,474 (275)

Estimating uveal melanoma volume with ellipsoid tumour models

open access: yesActa Ophthalmologica, Volume 103, Issue 6, Page 691-698, September 2025.
Abstract Purpose Ellipsoid tumour models are used to approximate the tumour volume of uveal melanomas, as the conventionally used ultrasound does not provide a three‐dimensional visualization of the tumour. However, these models are a simplification of the actual tumour geometry.
Lisa Klaassen   +3 more
wiley   +1 more source

Improving the Care Outcomes of Traumatic Enucleation with Artificial Eye Implant: a case report [PDF]

open access: green
Olumide Thomas Adeleke   +3 more
openalex   +1 more source

Germline Cancer Susceptibility Variants in Patients With Uveal Melanoma

open access: yesPigment Cell &Melanoma Research, Volume 38, Issue 5, September 2025.
Germline exome sequencing of 106 Finnish patients with UM, considered at higher risk for genetic cancer predisposition, identified pathogenic or likely pathogenic variants associated with varying risk of malignancies in 16 patients (15%). Six patients (6%) carried multiple variants and had a median diagnosis age of 51, compared to 60 in the full cohort
Pauliina E. Repo   +10 more
wiley   +1 more source

Erchen Decoction Offers Health Benefits in Regulating Obesity: Component Analysis, Network Pharmacology, and Experiment Verification

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
This study explored the potential of Erchen Decoction (ECT) in treating simple obesity by integrating network pharmacology, molecular docking, and animal experiments. ECT was found to regulate lipid metabolism, oxidative stress, and immune responses, with key compounds exhibiting strong binding to oxidative stress and immune markers. Animal experiments
Longfei Zhang   +9 more
wiley   +1 more source

Medulloepithelioma of the ciliary body

open access: yesIndian Journal of Ophthalmology, 2002
A rare case of medulloepithelioma of the ciliary body is described. The tumour necessitated enucleation of the eye; histopathological diagnosis was benign nonteratoid medulloepithelioma of the ciliary ...
Al-Torbak Abdullah   +3 more
doaj  

“That's All Anyone Needs Really, Support”: A Content Analysis of Retinoblastoma Survivors’ Psychosocial Support Needs

open access: yesPediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Retinoblastoma (Rb) is a rare intraocular malignancy that affects one in 23,000 children born in the UK each year. This cancer can impact survivors across their lifetime, with the specific psychosocial challenges affecting this group becoming increasingly understood.
Nicola O'Donnell   +3 more
wiley   +1 more source

PD‐L1 Promotes Immunological Tolerance and Enhances Visual Protection of hESC‐RPE Grafts in Retinal Degeneration

open access: yesCell Proliferation, Volume 58, Issue 8, August 2025.
We generated immune‐tolerant mature hESC‐RPE cells by overexpressing PD‐L1. PD‐L1‐expressing hESC‐RPE grafts exhibited significantly higher survival, reduced apoptosis and enhanced visual protection in retinal degeneration models, which presents an alternative target to improve the efficiency of hESC‐RPE‐based therapy for AMD. ABSTRACT Immune rejection
Bowen Li   +11 more
wiley   +1 more source

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