Results 41 to 50 of about 1,630,283 (259)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

කම්පනයකට මුහුණ දී සිටින්නන්ගෙන් ප්‍රකාශයන් ලබා ගැනීමේදී සැලකිලිමත් විය යුතු කරුණු

open access: yes, 2023
This entry includes 5 infographics (in Sinhala).On August 31, 2023, Ethics Eye published media ethics guidelines for obtaining statements from affected ...
Ethics Eye
core   +1 more source

Clinical Characteristics, Histopathology, and Treatment Outcomes of Pythium Keratitis: A Retrospective Cohort Study

open access: yesClinical Ophthalmology, 2021
Vilavun Puangsricharern,1,2 Patraramon Chotikkakamthorn,2 Wasee Tulvatana,1 Thanachaporn Kittipibul,2 Patchima Chantaren,2 Usanee Reinprayoon,2 Ngamjit Kasetsuwan,1,2 Vannarut Satitpitakul,2 Navaporn Worasilchai,3,4 Ariya Chindamporn3 1Department of ...
Puangsricharern V   +9 more
doaj  

Endogenous Panophthalmitis in a case of Multiple Myeloma and Diabetes Mellitus [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Multiple myeloma cripples the human body in many ways, one of them being decreased immunity. Infections occurring spontaneously can increase the morbidity. We report a case of an elderly lady with multiple myeloma on treatment and uncontrolled diabetes,
Madhurima K. Nayak, Neha Singh
doaj   +1 more source

Viral Infection and Antiviral Treatments in Ocular Pathologies

open access: yesMicroorganisms, 2022
Ocular viral infections are common and widespread globally. These infectious diseases are a major cause of acute red eyes and vision loss. The eye and its nearby tissues can be infected by several viral agents, causing infections with a short course and ...
Francesco Petrillo   +5 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

The Emergence Potential of Chlamydia psittaci and Chlamydia felis as Zoonotic Agents Causing Ocular and Respiratory Infections in Humans and Animals [PDF]

open access: yesArchives of Razi Institute
Members of the Chlamydiaceae are obligate Gram-negative intracellular pathogens causing panoply of infectious diseases. As a zoonotic pathogen, Chlamydia psittaci (C.
Majid Ghasemian   +5 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

An Analysis of the Use of Topical Ocular Anti-Infectives in Galicia (Spain) between 2020 and 2023

open access: yesDiseases
Eye infections are a global health and economic problem that affect people of both sexes at any age. Topical application of anti-infectives is widely used in the treatment of these types of infections.
Severo Vázquez-Prieto   +2 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

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