Results 191 to 200 of about 1,715,675 (251)
Advanced Science, EarlyView.In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen +12 more
wiley +1 more source
Advanced Science, EarlyView.Hederagenin is identified as a GABAA1‐targeting natural compound that suppresses morphine‐associated reward by restraining Ca2+–CaMK–cAMP–CREB signaling in ventral tegmental dopaminergic neurons. RVG29‐modified liposomal delivery further enhances brain accumulation and behavioral efficacy, providing a mechanistically defined strategy for natural ...
Hongyang Jiang +15 more
wiley +1 more source
ව්යසනයක් අතරතුර වාර්තා කටයුතුවල නිරත වීමට මාධ්යවේදීන් සඳහා ප්රවේශයක්
This entry includes 4 infographics with 1 writeup (Both in Sinhala).On June 03, 2024, the Ethics Eye team published a set of guidelines to be followed when reporting on disaster ...
Ethics Eye
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A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior
Advanced Science, EarlyView.Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li +12 more
wiley +1 more source
Management of a Penetrating Orbital Trauma from an Unusual Foreign Body with Associated Eye Injury. [PDF]
Ann Maxillofac Surg, 2019 Fernández-Ferro M +4 more
europepmc +1 more source
ඔබ දැන සිටියාද දිවි තොර කර ගැනීම් වසංගතයක් ලෙසින් පැතිර යාමට ඉඩ ඇති බව ...
This entry includes four infographics in Sinhala.On 10 September 2024, the Ethics Eye team published a four-slide post offering guidance to media professionals on the importance of adhering to ethical guidelines when reporting on ...
Ethics Eye
core
Closing the Loop: High‐Precision 3D Photofabrication in Living Tissues
Advanced Science, EarlyView.Writing 3D microstructures inside living tissue demands more than laser access; It demands information. Hierarchical sensing captures thermal and mechanical states across pulse‐train, voxel, and structure timescales, feeding a controller that steers the laser in real time.
Amirbahador Zeynali +2 more
wiley +1 more source
Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism
Advanced Science, EarlyView.Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He +7 more
wiley +1 more source
Conjunctival Limbal Autograft Combined with Amniotic Membrane Transplantation to Treat a Moderate Chemical Eye Injury. [PDF]
Beyoglu Eye J, 2019 Cankaya C.
europepmc +1 more source