Results 61 to 70 of about 50,239 (277)

Surfactant cocamide monoethanolamide causes eye irritation by activating nociceptor TRPV1 channels [PDF]

, 2021
Fang Zhao, Shuangyan Wang, Yan Li, Jin Wang, Yujing Wang, Chunlei Zhang, Yong Li, Longjiang Huang, Ye Yu, Jie Zheng, Boyang Yu, Isaac N. Pessah, Zhengyu Cao   +12 more
openalex   +1 more source

Comparative study between smokers and nonsmokers regarding dry eye

Delta Journal of Ophthalmology, 2018
Purpose The purpose of this study was to evaluate the relationship between smoking and dry eye in the adult population. Patients and methods A total of 500 male patients, 250 smokers and 250 nonsmokers, were recruited for this study in the period ...
Hosam Eldine Mohamed Khalil, Safaa Awadallah Aboud, Mostafa Amer Azzab   +2 more
doaj   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source

NIR‐Activatable Domino Cascade Catalysis Nanozyme Reactor for Multi‐Mechanism Synergistic Immunotherapy in Bladder Cancer

Advanced Science, EarlyView.
This study presents an intravesical delivery strategy of ferroptosis‐ and immunity‐inducing nanozyme‐loaded thermoresponsive hydrogels (FMCC@PNH) for enhanced bladder cancer therapy. Abstract Current intravesical therapies for bladder cancer after resection are limited by poor tissue penetration, off‐target effects, and insufficient efficacy.
Yongnan Jiang, Qingling Zhang, Yuhan Zhang, Xinlu Yu, Bo Jia, Yulong Dong, Yalong Wu, Kelong Fan, Xinquan Gu, Lei Ji, Wei Jiang, Bin Liu   +11 more
wiley   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

Advanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen, Ioannis Ziogas, Shirina Alsaedi, Mouza Alshehhi, Shahd Almheiri, Adil Rehman, Khulood Al Shehhi, Hani Saleh, Ahsan Khandoker, Charalampos Pitsalidis, Antoun Khawaja, Anna‐Maria Pappa   +11 more
wiley   +1 more source

Preparation and Evaluation of Topically Applied Azithromycin Based on Sodium Hyaluronate in Treatment of Conjunctivitis

Pharmaceutics, 2019
Azithromycin (AZI) eye drops containing sodium hyaluronate (SH) were developed to improve the bioavailability of AZI. Interaction between AZI and SH in the AZI-SH formulation was investigated by differential scanning calorimetry, X-ray diffraction, and ...
Qian Chen, Chun Yin, Jiang Ma, Jiasheng Tu, Yan Shen   +4 more
doaj   +1 more source

Influence of the Degree of Substitution of Carboxymethyl Cellulose Binders on the Properties and Performance of Aqueously Processed LiNi0.6Mn0.2Co0.2O2‐Based Positive Electrodes—A Comparative Study

Advanced Energy and Sustainability Research, EarlyView.
Aqueous processing of positive electrodes is a crucial step toward sustainable production of lithium ion batteries. Therein, the individual properties of the binding agent can largely influence processing, the physical electrode properties, and thus, the electrochemical performance and cycle life.
Johanna Kauling, Chirag Vankani, Martin Winter, Markus Börner   +3 more
wiley   +1 more source

Efficacy and local irritation evaluation of Eriobotrya japonica leaf ethanol extract

Laboratory Animal Research, 2019
Background Although Eriobotrya japonica leaves have been studied as a raw material for various cosmetic products, little is known about the anti-oxidant, anti-inflammatory, and anti-melanogenic activities of Eriobotrya japonica leaf ethanol extract (EJEE)
Nak-Won Seong, Won-Jun Oh, Il-Soo Kim, Su-Jin Kim, Ji-Eun Seo, Chang-Eon Park, Da-Young Kim, Je-Won Ko, Jong-Choon Kim   +8 more
doaj   +1 more source