Results 91 to 100 of about 795,560 (282)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Analyzing the Impact of Cognitive Load in Evaluating Gaze-based Typing

, 2017
Gaze-based virtual keyboards provide an effective interface for text entry by eye movements. The efficiency and usability of these keyboards have traditionally been evaluated with conventional text entry performance measures such as words per minute ...
Kumar, Chandan, Menges, Raphael, Sengupta, Korok, Staab, Steffen, Sun, Jun   +4 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

FocalVid: A Platform for Tracking Visual Attention to Video via Crowdsourcing Validated Against Human Gaze Data

IEEE Access
Human attention to dynamic visual stimuli can be measured using mouse-contingent cursor movements as a proxy for tracking human gaze when eye tracking is not feasible, for example, in online studies.
Sahand Shaghaghi, Karissa B. Payne, Bryan Tripp, Kerstin Dautenhahn, Chrystopher L. Nehaniv   +4 more
doaj   +1 more source

Anticipatory Eye Movements in Congkak

i-Perception, 2011
Congkak is a traditional Malaysian board game involving two players taking turns to pick up marbles from a series of holes on the board. We used this game as a model to explore the role of anticipatory eye movements during natural actions (in this case ...
Sheryl Chong, Neil Mennie
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Continuous Auditory Feedback of Eye Movements: An Exploratory Study toward Improving Oculomotor Control

Frontiers in Neuroscience, 2017
As eye movements are mostly automatic and overtly generated to attain visual goals, individuals have a poor metacognitive knowledge of their own eye movements.
Eric O. Boyer, Jean Lorenceau, Arthur Portron, Frederic Bevilacqua   +3 more
doaj   +1 more source

Miniature Eye Movements Enhance Fine Spatial Details [PDF]

, 2006
Our eyes are constantly in motion. Even during visual fixation, small eye movements continually jitter the location of gaze. It is known that visual percepts tend to fade when retinal image motion is eliminated in the laboratory.
Lovin, Ramon, Poletti, Martina, Rucci, Michele, Santini, Fabrizio   +3 more
core   +1 more source

Motion transparency : depth ordering and smooth pursuit eye movements [PDF]

, 2011
When two overlapping, transparent surfaces move in different directions, there is ambiguity with respect to the depth ordering of the surfaces. Little is known about the surface features that are used to resolve this ambiguity.
Schütz, Alexander C.
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source