Results 41 to 50 of about 626,683 (259)

Ion Movement in the Eye [PDF]

Circulation, 1960
The optical integrity and the metabolism of the eye depend on the exchange of substances between the blood vessels of the eye and the ocular chambers. The present paper considers the exchange of 3 ions in particular, i.e., sodium, chloride and bicarbonate, in the eye, with particular reference to the role of diffusion and active transport in ...
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Temporal Patterns of Saccadic Eye Movements Predict Individual Variation in Alternation Rate during Binocular Rivalry

i-Perception, 2012
Interindividual variation has been shown in the rates at which subjects alternate in perception during viewing of binocular rivalry and other ambiguous figures. A similar pattern of interindividual variation is evident in the rate of eye movements.
Sarah Hancock, Lynn Gareze, John M Findlay, Timothy J Andrews   +3 more
doaj   +1 more source

Minimal hepatic encephalopathy is associated to alterations in eye movements

Scientific Reports, 2022
Minimal hepatic encephalopathy (MHE) is diagnosed using PHES battery, but other tests are more sensitive, and a simple tool for early MHE detection is required.
Franc Casanova-Ferrer, Cecilia E. García-Cena, Juan-Jose Gallego, Alessandra Fiorillo, Amparo Urios, Alberto Calvo-Córdoba, Maria-Pilar Ballester, María Pilar Ríos, Lucía Durbán, Marta R. Hidalgo, Francisco García, Vicente Felipo, Carmina Montoliu   +12 more
doaj   +1 more source

Recent Saccadic Eye Movement Research Uncovers Patterns of Cognitive Dysfunction in Schizophrenia. [PDF]

, 2001
The frontal cortex and the subcortical areas of the brain play a major role in the control of thought and action. Eye movements are increasingly used in neuropsychological research to explore the executive and sensorimotor functions of such neural ...
Broerse, Annelies, Crawford, Trevor J.
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Simple Wearable Eye Tracker With Mini-Infrared Point Sensors

IEEE Access
In this study, we developed a wearable eye tracker leveraging mini-infrared point sensors. The eye tracker utilized two inexpensive mini-infrared ray (IR) point sensors to measure the left-right eye movements of both eyes. These left-right eye movements,
Sung Jae Chang, Ji-Yeon Lee, Soo-Il Kim, Sang-Yun Lee, Dong Woo Lee   +4 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source