Results 151 to 160 of about 9,100,105 (363)
Structured Lipids: Synthesis, Genetic Engineering, and Applications
Journal of the American Oil Chemists' Society, EarlyView.ABSTRACT Lipids are essential to the human body, but some can be harmful. As a result, current research focuses on structured lipids (SLs), which are engineered to have specific fatty acid arrangements. These structural modifications can enhance both nutritional and physical properties.
Chandu S. Madankar +5 more
wiley +1 more source
Painless Mass on the Eyelid: Kimura Disease
Beyoglu Eye JournalKimura disease (KD) is a rare chronic inflammatory disease of unknown etiology. It usually presents with regional lymphadenopathy in the head-and-neck region and swelling of the salivary glands and subcutaneous tissues. Periocular involvement in KD is rare. We report a case of KD on the eyelid as a rare cause of eyelid masses.
Nilay, Yuksel +2 more
openaire +2 more sources
Assessment of Anticancer Effects of Aloe vera on 3D Liver Tumor Spheroids in a Microfluidic Platform
Biotechnology and Bioengineering, EarlyView.The comparative effects of Doxorubicin and Aloe vera on HepG2 spheroids grown in a microfluidic device are illustrated in the graphical abstract. In the upper panel, red markers indicate that Doxorubicin treatment primarily induces necrosis in the spheroids.
Atakan Tevlek +2 more
wiley +1 more source
Pyoderma gangrenosum of the eyelid associated with inflammatory bowel disease
, 2020 Larissa A. Habib +5 more
openalex +1 more source
ChemMedChem, EarlyView.The synthesis of a new series of 4,5‐dihydrothiazol‐2‐ylphenylpiperazine derivatives as serotoninergic ligands is described and tested for their affinity toward 5‐HT1A, 5‐HT2A,and 5‐HT2C and selected for further in vivo assays to determine their functional activity. The pharmacological studies highlight that among the developed derivatives, FG‐7 and FG‐
Giorgia Andreozzi +18 more
wiley +1 more source
ChemMedChem, EarlyView.The work presents details of the efforts to design and characterize novel D4 inhibitors. A new 4,4‐difluoropiperidine ether series that confers improved potency and selectivity for D4 versus the other dopamine receptor subtypes is identified. Extensive structure‐activity relationship around this privileged group identifies the key structural changes to
Saeedeh Saeedi +3 more
wiley +1 more source
Harnessing Viral Proteases for Cellular and Molecular Engineering
Chemistry–Methods, EarlyView.Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui +2 more
wiley +1 more source
ChemSusChem, Accepted Article.Thalassemias are a group of inherited haemoglobinopathies that disrupt normal haemoglobin synthesis. Managing these conditions often involves regular blood transfusions and iron chelation therapy to mitigate iron overload. Among the available chelators, deferoxamine, deferasirox, and deferiprone, the latter stands out notably for its use when other ...
Francesco Basoccu +6 more
wiley +1 more source